anterior horn cell


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anterior horn cell

[an¦tir·ē·ər ′hȯrn ‚sel]
(neuroscience)
A motor neuron in the anterior horn gray matter of the spinal cord; directly innervates skeletal muscle.
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In summary, our findings suggest that involvement of WNV with anterior horn cells, which resulted in a poliomyelitislike syndrome, represents the most common underlying cause of paralysis with WNV infection.
Clinical and electrodiagnostic data suggested the involvement of spinal anterior horn cells, resulting in a poliomyelitis-like syndrome.
2002; Nash, 2001) With bilateral flaccid paralysis, WNV attacks the anterior horn cells causing acute flaccid paralysis, resulting in a poliomyelitis-like syndrome (Li et al.
Inflammatory cells were clustered around dying anterior horn cells, which is an indication of neuronophagia.
Destruction of the spinal anterior horn cells may cause acute flaccid paralysis (AFP), presenting as asymmetric limb weakness, hypoflexia or areflexia, and acute bowel or bladder dysfunction that may appear without signs of meningoencephalitis.
In the cases of WNV-associated AFP, clinical, laboratory, and electrophysiologic findings suggested pathology localized to anterior horn cells and motor axons, similar to that seen in acute poliomyelitis.
The poliovirus infects the spinal cord anterior horn cells and other motor neuron cells.
Similarly, as the passing decades result in gradual degeneration of the anterior horn cells and decreases in muscle mass and the size of muscle fibers, and when blood circulation within the cord diminishes, spasticity may decrease somewhat.

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