Anthelmintic

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anthelmintic

[¦an·thel¦min·tik]
(pharmacology)

Anthelmintic

 

(also vermifuge, helminthagogue), a preparation used to treat worm diseases, or helminthiases. The action of different anthelmintics varies. Some preparations, such as Heptylresorcine and Phenasal, damage the cuticle (integument) of helminths, while other preparations, such as santonin, ditrazin, piperazine, and naphtammone, alter the tone and mobility of parasites. Anthelmintics expel helminths from the patient’s body and are used when helminths infest the intestine and its communicating organs (liver, pancreas). Anthelmintics are also used to kill helminths.

Piperazine acts on the neuromuscular system of ascarids, which are subsequently excreted with feces. Phenasal destroys the integument of various tapeworms, including beef tapeworms, dwarf tapeworms, and broad tapeworms. They are then digested in the intestine and their residue is excreted. Chloxyl kills Siberian liver fluke in the liver and pancreas. The parasite is then eliminated into the intestine. Other anthelmintics, such as ditrazin and antimony preparations, destroy helminths, such as filiariae and schistosomes, in the blood, lymphatics, and tissues. Some antihelmintics, such as ditrazin and Chloxyl, are produced chemically. Others are obtained from plants, for example, from Artemisia cina or the extract of male fern.

REFERENCE

Krotov, A. I. Osnovy eksperimental’noi terapii gel’mintozov. Moscow, 1973.

N. N. PLOTNIKOV

References in periodicals archive ?
LECTURER Dr Philip Cain TALK Gillian Butler will raise her concerns over resistance to anthelminthics ENTHUSIAST Andrew Jamieson, a rural business consultant at George F White is urging farmers to attend the agricultural seminars ANIMAL WELFARE The subject of worm resistance will be addressed at the seminar
Such decrease in overall total protein content was observed due to the treatment of anthelminthics on Anguilicola crassus of eel (Geets et al.
19, 22) Less than half (31%) of mothers sought treatment from hospital and this could be due to illiteracy on worm's infection which in turn might have greatly attributed to the lack of knowledge on anthelminthics.