Anthelmintic

(redirected from anthelmintic resistance)
Also found in: Dictionary, Thesaurus, Medical.
Related to anthelmintic resistance: Anthelmintics

anthelmintic

[¦an·thel¦min·tik]
(pharmacology)

Anthelmintic

 

(also vermifuge, helminthagogue), a preparation used to treat worm diseases, or helminthiases. The action of different anthelmintics varies. Some preparations, such as Heptylresorcine and Phenasal, damage the cuticle (integument) of helminths, while other preparations, such as santonin, ditrazin, piperazine, and naphtammone, alter the tone and mobility of parasites. Anthelmintics expel helminths from the patient’s body and are used when helminths infest the intestine and its communicating organs (liver, pancreas). Anthelmintics are also used to kill helminths.

Piperazine acts on the neuromuscular system of ascarids, which are subsequently excreted with feces. Phenasal destroys the integument of various tapeworms, including beef tapeworms, dwarf tapeworms, and broad tapeworms. They are then digested in the intestine and their residue is excreted. Chloxyl kills Siberian liver fluke in the liver and pancreas. The parasite is then eliminated into the intestine. Other anthelmintics, such as ditrazin and antimony preparations, destroy helminths, such as filiariae and schistosomes, in the blood, lymphatics, and tissues. Some antihelmintics, such as ditrazin and Chloxyl, are produced chemically. Others are obtained from plants, for example, from Artemisia cina or the extract of male fern.

REFERENCE

Krotov, A. I. Osnovy eksperimental’noi terapii gel’mintozov. Moscow, 1973.

N. N. PLOTNIKOV

References in periodicals archive ?
An inconvenient truth: Global warming and anthelmintic resistance.
A comparison of in vitro tests and a faecal egg count reduction test in detecting anthelmintic resistance in horse strongyles.
a range of tactics to delay anthelmintic resistance.
Importance of chemotherapy cannot be flouted in spite of certain concerns like: anthelmintic resistance (Waller, 2006), which is very common in goats (Zajac and Gipson, 2000), higher cost of therapy, and drug residues in meat and milk of the treated animals (Kaufmann et al.
Rachel said: "As sheep farm productivity has already been devastated by anthelmintic resistance, it is essential we take all measures to slow its spread.
Mechanism of development of anthelmintic resistance
Keywords: Sheep, anthelmintic resistance, Oxfendazole, Levamisole, Ivermectin, Haemonchus contortus, Trichostrongylus, Nematodirus, Ostertagia.
In 2006 a Wales Worm Watch study detected anthelmintic resistance on 82% of the 122 farms tested.
The anthelmintic resistance was detected in gastrointestinal (HPG) nematodes (RHEH) against Albendazole in hair lambs of a Venezuelan flock, through of faecal egg count reduction test.