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(also vermifuge, helminthagogue), a preparation used to treat worm diseases, or helminthiases. The action of different anthelmintics varies. Some preparations, such as Heptylresorcine and Phenasal, damage the cuticle (integument) of helminths, while other preparations, such as santonin, ditrazin, piperazine, and naphtammone, alter the tone and mobility of parasites. Anthelmintics expel helminths from the patient’s body and are used when helminths infest the intestine and its communicating organs (liver, pancreas). Anthelmintics are also used to kill helminths.

Piperazine acts on the neuromuscular system of ascarids, which are subsequently excreted with feces. Phenasal destroys the integument of various tapeworms, including beef tapeworms, dwarf tapeworms, and broad tapeworms. They are then digested in the intestine and their residue is excreted. Chloxyl kills Siberian liver fluke in the liver and pancreas. The parasite is then eliminated into the intestine. Other anthelmintics, such as ditrazin and antimony preparations, destroy helminths, such as filiariae and schistosomes, in the blood, lymphatics, and tissues. Some antihelmintics, such as ditrazin and Chloxyl, are produced chemically. Others are obtained from plants, for example, from Artemisia cina or the extract of male fern.


Krotov, A. I. Osnovy eksperimental’noi terapii gel’mintozov. Moscow, 1973.


References in periodicals archive ?
A compelling reason for Panlatinga's participation was the high level of anthelmintic resistance on the property which receives 520 mm of rainfall a year.
This year HCC will be focussing on anthelmintic resistance, with advice on worming treatments.
While the problem does not fortunately seem to have taken a firm hold among cattle, there have been cases of anthelmintic resistance and it is a situation of which all dairy producers need to be aware, says independent veterinary consultant Tony Andrews in his foreword of the Cows (Control of Worms Sustainably) project.
The Wales Against Anthelmintic Resistance Development (WAARD) project says the results are worrying, with parasites on four farms found to be resistant to all of the wormers tested.
The group recognised that we are now not in a position to prevent anthelmintic resistance, but that we should aim to avoid wide-scale resistance.
This can reduce wormer usage and save money, slow the development of anthelmintic resistance and enhance the growth potential of animals.
Anthelmintics are essential for worm control and to avoid anthelmintic resistance developing through frequent use and mis-use a strategy must be developed.
Greater take-up of take up animal health planning and more industry-funded work to overcome anthelmintic resistance.