androgen

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androgen

(ăn`drəjən): see testosteronetestosterone
, principal androgen, or male sex hormone. One of the group of compounds known as anabolic steroids, testosterone is secreted by the testes (see testis) but is also synthesized in small quantities in the ovaries, cortices of the adrenal glands, and placenta, usually
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Androgen

One of a class of steroid hormones. Androgens play a major role in the development and maintenance of masculine secondary sexual characters, for example, the seminal vesicle and prostate gland of the male mammal, and the comb, wattles, and spur of the male fowl. They also influence certain other secondary sexual characters, such as hair growth pattern and voice quality in humans. In the fowl, they affect the pattern and seasonal coloration of its feathers, as well as crowing. In addition, androgens affect nitrogen metabolism (anabolic). Androgens are produced in the testis, ovary, adrenal, and most likely, in the placenta. A small portion of the androgen is from corticoids, or adrenal cortex steroids, and from other C21 steroids, such as progesterone. See Hormone, Ovary, Progesterone, Steroid, Testis

McGraw-Hill Concise Encyclopedia of Bioscience. © 2002 by The McGraw-Hill Companies, Inc.

androgen

[′an·drə·jən]
(biochemistry)
A class of steroid hormones produced in the testis and adrenal cortex which act to regulate masculine secondary sexual characteristics.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Finally, 8 pesticides that were newly described as highly active antiandrogens in the MDA-kb2 assay and 4 pesticides for which the QSAR prediction differed from the experimental result (including 1 out of the model domain) were subjected to further testing using the YAS (n =14).
The abnormal development of male sex organs in the rat using a pure antiandrogen and a 5 alpha-reductase inhibitor during gestation.
Consequently, measurement of AGD is considered to be a sensitive index of prenatal androgen action and hence could be used in humans as a marker of the antiandrogen effects of EDCs.
"When you're giving antiandrogen drugs, you should probably monitor for torsade de pointes and be very careful about controlling the other risk factors for QT prolongation," Salem said.
Oral contraceptives are the best first-line treatment for mild to moderate hirsutism and can be used in combination with antiandrogens or other therapies8.
Topical agents that release nitric oxide locally or target sebum by inhibiting acetyl coenzyme-A carboxylase, as well as a topical antiandrogen are in clinical trials.
We have previously shown that in adolescent girls with PCOS, oral contraception (OC)--as compared to combined low-dose insulin sensitization plus antiandrogen therapy--is linked to a less favorable endocrine-metabolic profile [5, 6].
(12); radiation therapy, antiandrogen therapy, histologic subtype, necrosis rate, grade of sarcoma are not predictive to estimate overall survival.
See also Karen Harrison, Legal and Ethical issues when using Antiandrogenic Pharmacotherapy with Sex Offenders, 3 SEXUAL OFFENDER TREATMENT, 2008, http://www.sexualoffender-treatment.org/ 2-2008_01.html (citing antiandrogen use in California and Montana as mandated by legislature); Kris W.
Patients with a urinary tract infection, acute urinary retention, prostate cancer or neurogenic bladder, the use of [alpha]1-adrenoceptor antagonist or antiandrogen, and a history of prostatic surgery were excluded from this study.
Here, in this study, to aid the research and development of steroidal antiandrogens, we investigated the relationships between a series of 7[alpha]-substituted dihydrotestosterone derivatives and corresponding antiandrogen activities.