anticoagulant

(redirected from anticoagulant rodenticide)
Also found in: Dictionary, Thesaurus, Medical.
Related to anticoagulant rodenticide: diphacinone, warfarin poisoning

anticoagulant

(ăn'tēkōăg`yələnt), any of several substances that inhibit blood clot formation (see blood clottingblood clotting,
process by which the blood coagulates to form solid masses, or clots. In minor injuries, small oval bodies called platelets, or thrombocytes, tend to collect and form plugs in blood vessel openings.
..... Click the link for more information.
). Some anticoagulants, such as the coumarin derivatives bishydroxycoumarin (Dicumarol) and warfarin (Coumadin) inhibit synthesis of prothrombin, a clot-forming substance, and other clotting factors. The coumarin derivatives compete with vitamin K, which is a necessary substance in prothrombin formation (see vitaminvitamin,
group of organic substances that are required in the diet of humans and animals for normal growth, maintenance of life, and normal reproduction. Vitamins act as catalysts; very often either the vitamins themselves are coenzymes, or they form integral parts of coenzymes.
..... Click the link for more information.
). They are only effective after the body's existing supply of prothrombin is depleted. Another anticoagulant, heparin, is a polysaccharide (see carbohydratecarbohydrate,
any member of a large class of chemical compounds that includes sugars, starches, cellulose, and related compounds. These compounds are produced naturally by green plants from carbon dioxide and water (see photosynthesis).
..... Click the link for more information.
) found naturally in many cells. It acts in several ways: by preventing prothrombin formation; by preventing formation of fibrin, another clotting substance; and by decreasing the availability of a third clotting factor, thrombin. Heparin is obtained by extracting it from animal tissues. Anticoagulants are used to treat blood clots, which appear especially frequently in veins of the legs and pelvis in bedridden patients. Therapy helps to reduce the risk of clots reaching the lung, heart, or other organs. Heparin causes an instantaneous increase in blood-clotting time, and its effect lasts several hours.

anticoagulant

[¦an·tē‚kō′ag·yə·lənt]
(pharmacology)
An agent, such as sodium citrate, that prevents coagulation of a colloid, especially blood.

anticoagulant

1. acting to prevent or impair coagulation, esp of blood
2. an agent, such as warfarin, that prevents or impairs coagulation
References in periodicals archive ?
On day 2, the results of the deceased mate's blood anticoagulant rodenticide screen confirmed the presence of brodifacoum at 0.005 ppm.
Chocolate brown blood may indicate methemoglobinemia; watery not coagulable blood and bleeding from the venepuncture site suggest anticoagulant rodenticides (Patterino et al., 2004).
DEC analytical laboratories in Gloversville and Rensselaer can test for organochlorine pesticides like DDT and anticoagulant rodenticides in wildlife.
In the TPIC's experience the most common exposures involve paracetamol and household pesticides such as anticoagulant rodenticides, pyrethroids, some cholinesterase inhibitors and irritant/ corrosive cleaning agents, all of which are readily accessible on supermarket shelves.
Anticoagulant rodenticides, for the control of porcupine require long baiting periods and involve higher operational cost (Khan and Mian, 2008), while the fumigation of porcupine burrows is only feasible in the loamy soils (Mushtaq et al., 2008).
Anticoagulant rodenticides, commonly known by trade names such as D-Con, kill rodents by causing their blood to stop clotting so that they bleed out three or four days after eating the poison.
Popular brands that contain anticoagulant rodenticides are: Havoc, Liqui-Tox II, Final Blox, d-Con, Contrac, Enforcer, Farnam Just One Bite, and Tomcat.
The most common pesticide exposures across all age groups were cholinesterase inhibitors (25.3%), anticoagulant rodenticides (20.5%) and pyrethroids (14.4%).
In 1995, most persons who reported exposure to anticoagulant rodenticides did not develop symptoms or require specific therapy.
Earlier this month, VCWPA presented data from its Raptor Study for Levee Protection on using hawks and owls to control rodents, showing that raptor-friendly habitats reduce ground squirrel burrowing damage by 50 percent when compared to using anticoagulant rodenticides. The VCPWA study marks the first time any agency has quantified the impact of birds of prey on rodents in public works projects.

Full browser ?