Anticonvulsant


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anticonvulsant

[‚an·tē·kən′vəl·sənt]
(pharmacology)
An agent, such as Dilantin, that prevents or arrests a convulsion.

Anticonvulsant

 

one of a group of medicinal preparations having different chemical compositions and capable of preventing or relieving convulsions. Anticonvulsants include a number of substances that act as hypnotics and sedatives, for instance, bromides, chloral hydrate, magnesium sulfate, and phenobarbital. Other substances are selectively anticonvulsant, for example, diphenin, Hexamidine (lepsiral), Trimethin (epidione), and chloracon. Anticonvulsants are used mainly in treating epilepsy.

REFERENCE

Mashkovskii, M. D. Lekarstvennye sredstva, 7th ed., part 1. Moscow, 1972.
References in periodicals archive ?
(2,12,17) Various anticonvulsant medications including valproic acid, carbamazepine, and phenytoin have been reported as potentially helpful in the treatment of these disorders.
Galanin, a neuropeptide, possesses both anticonvulsant and antiepileptogenic activity when injected directly into the brain.
Despite the boost in longevity that the anticonvulsant drugs yielded in worms, Kornfeld cautions that a similar effect has not been documented in people.
It doesn't make sense to put every child who has had a seizure on anticonvulsant medication.
The other group had their anticonvulsant drugs changed before conception and took folic acid throughout pregnancy.
Most commonly found were anti-inflammatory and pain-killing drugs, cholesterol-lowering drugs, anticonvulsants, and sex hormones from oral contraceptives.
The man was prescribed bromazepam (1.5 mg ql2h po) and the anticonvulsant carbamazepine (200 mg q12h po).
Among these are two mood-stabilizing anticonvulsants, carbamazepine (Tegretol[R]) and valproate (Depakote[R]).
Like other anticonvulsant drugs, carbamazepine acts by suppressing electrical activity in the brain.
The MES- and PTZ-induced convulsions are the basic and preliminary studies for establishing anticonvulsant activity to any substance.
"We discovered that cilantro, which has been used as a traditional anticonvulsant medicine, activates a class of potassium channels in the brain to reduce seizure activity," explains Geoff Abbott, principle investigator on the study.
In the present study, we investigated the anticonvulsant effects of the VHE and its ethyl acetate (EAF) and n-butanol (NBF) fractions on seizure models induced by PTZ and MES.