antidiuretic hormone


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antidiuretic hormone

(ăn'tēdīyo͞orĕt`ĭk), polypeptide hormone secreted by the posterior pituitary glandpituitary gland,
small oval endocrine gland that lies at the base of the brain. It is sometimes called the master gland of the body because all the other endocrine glands depend on its secretions for stimulation (see endocrine system).
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. Its principal action is to regulate the amount of water excreted by the kidneys. Antidiuretic hormone (ADH), known also as vasopressin, causes the kidneys to resorb water directly from the renal tubules, thus concentrating the salts and waste products in the liquid, which will eventually become urine. ADH secretion by the pituitary is regulated by neural connections from the hypothalamus, which is believed to monitor either the volume of blood passing through it or the concentration of water in the blood. Dehydration or body stress will raise ADH secretion and water will be retained. Alcohol inhibits ADH secretion. Failure of the pituitary to produce ADH results in diabetes insipidus. In pharmacological doses ADH acts as a vasoconstrictor. The structure and chemical synthesis of ADH was announced (1953) by Nobel laureate Vincent Du Vigneaud and others.
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antidiuretic hormone

[¦an·tē‚dī·yə¦red·ik ′hȯr‚mōn]
(biochemistry)
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
References in periodicals archive ?
Use of conivaptan for refractory syndrome of inappropriate secretion of antidiuretic hormone in a pediatric patient.
Incidence of selective serotonin reuptake inhibitor (SSRI) induced hyponatraemia due to the syndrome of inappropriate antidiuretic hormone (SIADH) secretion in the elderly.
Catalano, "Syndrome of Inappropriate Antidiuretic Hormone Associated with Escitalopram Therapy," CNS Spectrums, vol.
Findling, "Case report: renal phosphate wasting, syndrome of inappropriate antidiuretic hormone, and ectopic corticotropin production in small cell carcinoma," The American Journal of the Medical Sciences, vol.
ADH, plasma antidiuretic hormone; HCTZ, hydrochlorothiazide; SP, spironolactone; TCM, tri-chlormethiazide; IDM, indomethacin.
[1] Pinak Dutta I, Girish Parthan, Anuradha Aggarwal et al., "Amiodarone Induced Hyponatremia Masquerading as Syndrome of Inappropriate Antidiuretic Hormone Secretion by Anaplastic Carcinoma of Prostate," Case Reports in Urology, vol.
Miller, "Syndromes of excess antidiuretic hormone release," Critical Care Clinics, vol.
Hyponatremia is found in 20% of symptomatic AIP patients and is often due to SIADH (syndrome of inappropriate antidiuretic hormone).
The results of persistent secretion of AVP are clinical features similar to the syndrome of inappropriate secretion of antidiuretic hormone (SIADH).
Matsuda, "Small cell lung cancer accompanied by lactic acidosis and syndrome of inappropriate secretion of antidiuretic hormone," Lung Cancer, vol.