antifibrinolysin

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antifibrinolysin

[¦an·tē‚fī·brə′näl·ə·sən]
(biochemistry)
Any substance that inhibits the proteolytic action of fibrinolysin.
References in periodicals archive ?
As a synthetic antifibrinolytic agent, it can competitively inhibit the activation of plasminogen and noncompetitively inhibit the plasmin activity at high concentrations.
TABLE Facts about tranexamic acid * The dose is 1 g IV; it may be repeated once in 24 hours * Half-life is 2 hours * Clearance is renal--so do not use in patients with renal impairment * Antifibrinolytic activity usually lasts 7 to 8 hours * Tranexamic acid is contraindicated in patients with a history of thromboembolism in pregnancy * The drug is believed to be compatible with breastfeeding
10] General measures include antifibrinolytic therapy, e.
In anovulatory bleeding with stable patient, PG synthetase inhibitors such as mefenamic acid and antifibrinolytic drugs tranexamic acid were used as the first-line therapy for control of blood loss.
3] Studies have showed that antifibrinolytic therapy such as tranexamic acid, aminocaproic acid, recombinant factor VII, and platelet transfusions is the beneficial therapies for a patient with GT.
Antifibrinolytic medicines (including tranexamic acid and epsilon aminocaproic acid) may be used with replacement therapy.
As an antifibrinolytic agent, it prevents clot breakdown in the endometrium.
For this reason it has been proposed that tranexamic acid (a synthetic derivative of lysine) through its antifibrinolytic action may reduce the risk of PPH.
13) Tranexamic acid is a synthetic antifibrinolytic acid applied for the short-term control of bleeding.
Antifibrinolytic Agent--a medication that prevents the breakdown of fibrin in blood clots and is used to prevent excessive bleeding
In the post-operative period, she was on antifibrinolytic agents and to prevent any AUB and to delay her next cycle progesterone was started.