antifungal agent


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antifungal agent

[‚an·tē′fəŋ·gəl ‚ā·jənt]
(materials)
A chemical compound that either destroys or inhibits the growth of fungi.
References in periodicals archive ?
No well-designed, comparative study was identified that showed any oral antifungal agent to be superior to terbinafine in the treatment of dermatophytic skin infections.
Having haematological malignancy or non-albicans candida species, being in shock, having an absolute neutrophil count of less than 500, and not receiving timely antifungal agents were significantly associated with higher risk of mortality.
It is known that biofilms exhibit resistance against antifungals compared to planktonic cells; thus, the sub-inhibitory concentrations (1/2MIC, Table 1) of antifungal agents may have several important implications on planktonic cells destined to form biofilms.
Systemic antifungal agents have been recommended for patients with poor compliance such as patients with special needs.
Efinaconazole is an azole antifungal agent, with a mechanism of action identical to that of the systemic triazole agents discussed above--ie, inhibition of 14-alpha demethylase, with resulting downstream disruption of fungal cell membranes.
The study done by Paulose KO et al (4), Mohanty JC et al (5), Chander J et al (8) and Hurst WB et al (11) had followed thorough cleaning of ear meticulously before initiation of treatment and was comparable to the present study in which removal of the fungus and epithelial debris in the ear canal was done, followed by use of antifungal agent.
The increasing incidence of fungal infections without a satisfactory response to the current antifungal therapy and the slow development of new agents with novel mechanisms of action have produced significant interest on associations between antifungal agents.
Tokyo, Japan, Apr 21, 2006 - (JCN) - Dainippon Sumitomo Pharma announced on April 20 that it has received approval for AmBisome for Injection 50mg, a liposomal formulation of the antifungal agent amphotericin B, from the Ministry of Health, Labor and Welfare.
The percentage of isolates inhibited at each concentration of antifungal agent over the full dilution series is summarized in Table 2.
The other is ketoconazole (Nizoral), an antifungal agent.
relating to a generic version of Vfend[R] (voriconazole), an antifungal agent.
Serial twofold dilutions and final dilutions of each antifungal agent were prepared in RPMI 1640 medium.