antigen presentation


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Related to antigen presentation: clonal expansion, antigen recognition

antigen presentation

[¦an·tə·jən ‚prē·zən′tā·shən]
(immunology)
The process whereby a cell expresses antigen on its surface in a form that can be recognized by a T lymphocyte.
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Activated DCs acquire antigen presentation activity by increasing the expression of MHC-II and the T cell co-stimulatory molecules CD80 and CD86.
821 Mb and involved in the protein degradation and antigen presentation,[sup][40] suggesting a possible LD of the above SNPs with PD patients.
Unanue, "Identification of a macrophage antigen-processing event required for I-region-restricted antigen presentation to T lymphocytes," The Journal of Immunology, vol.
More recently, adipocytes were also found to express CD1d and a role in lipid antigen presentation has been suggested [6, 7].
MHC molecules play a role in antigen presentation captured by endo- or phagocytosis on the cell surface and, in contrast to monocytes or immature DCs (imDCs), are highly expressed on mDCs [9].
It is conceivable that dormant bacteria reside in cells which have a scarce ability to act as antigen presentation cells, and subverted macrophages in mature granulomas.
from Ohio State University in Immunology in 2007, where he studied the intersection of intracellular pathogens and the Class II antigen presentation pathway.
Other strategies, such as GM-CSF or interleukin-2, are pursued to increase immune cell availability in the tumor vicinity, and thus improve both antigen presentation and T-cell activation and proliferation.
8 per cent of the total set identified in the tissues, were involved in B cell and T cell activation and antigen presentation - key components of the adaptive immune response suggesting that koalas have the capability to protect themselves against microbial pathogens, such as Chlamydia.
In a bid to produce safe and immunologically active vaccines, the development of an "inactuated" vaccine by gamma irradiation whereby viral replication capability is lost yet, the structural integrity and transcriptional activity of the irradiated pathogen is retained to result in intracellular antigen presentation is proposed.
of Colorado, Boulder) simplifies the explanations presented in immunology texts by providing undergraduate and graduate students with 15 lectures that introduce components of the immune system and show how they interact in terms of the big picture, including B cells and antibodies, antigen presentation, T cells in action, secondary lymphoid organs and lymphocyte trafficking, tolerance induction and MHC (major histocompatibility complex proteins) restriction, the AIDS virus, autoimmune diseases, and allergies.
They are then combined with major histocompatibility complex molecules for antigen presentation to T cells.