accessory cell

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Related to Antigen-presenting cells: perforin, Dendritic cells

accessory cell

[ak′ses·ə·rē ‚sel]
(botany)
A morphologically distinct epidermal cell adjacent to, and apparently functionally associated with, guard cells on the leaves of many plants.
(immunology)
Any nonlymphocytic cell that helps in the induction of the immune response by presenting antigen to a helper T lymphocyte.
References in periodicals archive ?
"We found that when we gave the laboratory animals antibiotics, the antigen-presenting cells did not make IL-10.
The origin of these immature antigen-presenting cells is given in the bone marrow and migrates throughout the body.
DCs are professional antigen-presenting cells and essential mediators of innate and adaptive immune response, as well as tolerance [21].
Drosophila APCs have been demonstrated as effective antigen-presenting cells to stimulate naive CD8 T cells to generate CTLs in a clinical trial.
(22)-(24) For example, at Peyer's patches (PPs), which are well characterized GALT components, orally administered antigens are taken up by M cells located in the follicle-associated epithelium; M cells promptly deliver antigens to antigen-presenting cells, such as dendritic cells and macrophages, that lie beneath PPs.
The latter cells bind to MHC I on the antigen-presenting cells and destroy them, whereas the former contribute to immunological memory of the activation event.
The non-helper regulatory T cells, or the antigen-presenting cells (APC), likely influence immunity in a manner comparable to Th1 and Th2 cells.
While the exact mechanism is unknown, a large numbers of studies have shown that Ganoderma may modulate many components of the immune system such as the antigen-presenting cells, NK cells, T and B lymphocytesm, which are pivotal to initiating a primary immune response.
"It's mimicking some of the native molecules, but this turns out to be specific to antigen-presenting cells, endothelial cells, and monocytes," said Dr.
Expression of CD21 forms a complex with CD19 and CD81 to form the B cell coreceptor and it can serve as antigen-presenting cells, secrete cytokines, and differentiate into plasma cells that produce and secrete immunoglobulins (Foote et al., 2007).
For the study, pMHC molecules taken from a transgenic mouse were placed onto a red blood cell held by a micropipette, simulating the activity of antigen-presenting cells, which normally isolate these foreign molecules and display them for recognition by T cells.
There, protein fragments of the invading pathogen are displayed on the surface of antigen-presenting cells. Serving as a red flag, the fragments identify the bug and signal the immune system to attack cells infected by that agent.