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The authors conclude that these results suggest that coadministration of an antiinflammatory agent with the protein may improve its efficacy in ALS patients.
The drug is an antiinflammatory agent approved for the treatment of mild-to-moderate ulcerative colitis.
Analysis of the placebo-controlled, double-blind trial in individuals with muscle pain revealed clinically significant analgesic activity following treatment with a topical gel formulation of ibuprofen, a nonsteroidal antiinflammatory agent, containing MacroChem's patented skin absorption enhancer SEPA(R).