antimetabolite

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antimetabolite:

see metabolitemetabolite,
organic compound that is a starting material in, an intermediate in, or an end product of metabolism. Starting materials are substances, usually small and of simple structure, absorbed by the organism as food. These include the vitamins and essential amino acids.
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antimetabolite

[¦an·tē·mə′tab·ə‚līt]
(pharmacology)
A substance, such as sulfanilamide or amethopterin, that inhibits utilization of an essential metabolite because it is an analog of the metabolite.
References in periodicals archive ?
Nevertheless, since then, published reports from various medical fields, including dermatology (37), gynecology (38), and oncology (26), have collectively indicated that increased endogenous folate concentrations may indeed a priori neutralize the antimetabolic effect of MTX.
Seeds contain factors that are either antimetabolic compounds or elicitors of food allergies.
More specifically, the many antimetabolic tropes of King John condense and translate for auditors and readers the various mirrorings and impasses of this chronicle history that help create its characteristic indeterminate meaning.
In rats fed with experimental diet T2 containing raw SB seeds, a part of the protein supplied might be rerouted for the synthesis of digestive enzymes such as trypsin and chymotrypsin to offset the effects of various antimetabolic substances present in the raw SB seeds.
DPD is also the principal enzyme involved in detoxification of pyrimidine-based antimetabolic analogs, such as 5-fluorouracil (5-FU), a drug that is commonly used in the treatment of solid tumors (colon, breast, head, neck, ovary, and skin).