Placebo-controlled clinical trial of meglumine antimonate
A double-blind randomized clinical trial of a topical herbal extract (ZHE) vs systemic meglumine antimonate
for treatment of cutaneous leishmaniasis in Iran.
Since 1940, the pentavalent antimony compounds sodium stibogluconate and meglumine antimonate
have been the mainstays of leishmanial therapy [1,5,10,11].
tropica to glucantime (meglumine antimonate
) an antileishmanial agent, was also attributed to higher GSH levels (3).
Standard therapy for all forms of the disease is pentavalent antimony of sodium stibogluconate (Pentostam, GlaxoSmithKline) or meglumine antimonate
The patient's initial treatment included gluteal injections of meglumine antimonate
at a dosage of 20 mg antimony/kg/d intramuscularly for a total course of 21 days (LOE=5).
Besides antimony trioxide, Oxychem produces the flame retardants Dechlorane Plus, Pyronil 45, and sodium antimonate
. An aqueous dispersion of Dechlorane Plus and Fireshield H (antimony oxide) is now available from Oxychem, called Dechlorane Plus AD; this material is 67% active, containing a 3:1 ratio of Dechlorane Plus and Fireshield H.
For photoinitiation, a "hybrid" initiating system containing a fluorone dye initiator (DIBF), an onium salt (4-octyloxylphenyliodonium hexafluoro antimonate
, OPPI), and an amine (DIDMA) were used (26).
It operates an integrated copper smelter/lead refinery at Tsumeb which enables the recovery of by-products (silver, refined cadmium, refined arsenic trioxide and sodium antimonate