Preventing occupational exposures to antineoplastic drugs
in health care settings.
A meta-analysis of 14 studies, performed in 1966-2004 in the United States and Europe, described an association between exposure to antineoplastic drugs
and adverse reproductive effects on female healthcare workers .
Further, it might also be due to alteration in cell membrane permeability due to antineoplastic drugs
. Parallel finding have been reported by Brar and Sandhu (2000) in dogs affected with mammary tumour.
handling protection after OSHA guidelines.
Potential savings, however, may result from the decrease in serious adverse effects of cisplatin and other antineoplastic drugs
. This could reduce the use of costly antimicrobials, decrease the need for blood product transfusions and prevent some hospitalizations.
[25.] Valanis B.G., Vollmer W.M., Labuhn K.T., Glass A.G.: Association of antineoplastic drug
handling with acute adverse effects in pharmacy personnel.
With a wide range of complex and toxic drugs in use, it is essential adequate precautions are in place to protect both those administering and those receiving antineoplastic drugs
. These drugs vary widely in the complexity of the treatment regimen, the therapeutic window (the dose range that produces therapeutic response without having a significant adverse effect), the potential risk for patients and the recommended handling precautions.
[36.] Valanis B.G., Vollmer W.M., Labuhn K.T., Glass A.G.: Acute symptoms associated with antineoplastic drug
handling among nurses.
The lawsuits related to antineoplastic drugs
generate high costs for governments and demand detailed analyses to ensure an efficient use of public resources and positive outcomes for the health of citizens (2).
Day two included a Skype session on how patients in Southampton, in the United Kingdom, were receiving antineoplastic drugs
at home or at mobile centres in the community, if well enough after their first two cycles at hospital.
Part 2 covers vitamins, minerals, and herbs, skin medications, autonomic nervous system drugs, antineoplastic drugs
, urinary system drugs, GI drugs anti-infective drugs, eye medications, analgesics, sedatives, and hypnotics, psychotropic medications, alcohol, and drug abuse, musculoskeletal and anti-inflammatory drugs, anticonvulsants, antiparkinsonian drugs and agents for AlzheimerAEs disease, endocrine system drugs, reproductive system drug, cardiovascular drugs, respiratory system drugs and antihistamines, and drugs and older adults.
In terms of its structure, Cisplatin is an organo platinum compound that does not resemble other antineoplastic drugs
in terms of its structure.