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Further modifications of the antipyrine molecule aiming at improving its analgesic and antipyretic properties gave origin to various pharmaceuticals, such as aminophenazone (aminopiryne or amidopyrine), propyphenazone, dipyrone (metamizole), and phenylbutazone (1).
Banks, "Titanium nanoparticles (Ti[O.sub.2])/graphene oxide nanosheets (GO): An electrochemical sensing platform for the sensitive and simultaneous determination of benzocaine in the presence of antipyrine," Analyst, vol.
Sokoloff, "Measurement of local cerebral blood flow with iodo [14C] antipyrine," American Journal of Physiology Heart and Circulatory Physiology, vol.
Of note, the development of the concentration equilibrium of antipyrine in reverse perfusions was decelerated compared with perfusions in the M [right arrow] F direction (see Supplemental Material, Figure S3A,B).
Brocq in 1984, coined the term 'fixed eruption' to describe a specialized pattern of skin eruption due to antipyrine.  Fixed drug eruptions (FDE) is characterized by development of one or more annular or oval, sharply demarcated erythematous plaques or blisters as a result of systemic exposure to a drug, which usually leaves a residual hyperpigmentation.
The first reported case of fixed drug eruption by Bourns in 1889, described a series of sharply circumscribed, hyperpigmented lesions on the lips and tongue in a patient who had ingested antipyrine. Later, the French word "eruption erythemato-pigmentee fixe", was coined by Brocq to denote this type of lesion, which meant "fixed drug eruption".
Markers, such as tritium and deuterium oxide (heavy water), antipyrine and ethanol, for example, can be used to estimate total body water.
Plasma glucose was determined by the enzymatic (GOD-PAP, Glucose Oxidase-Amino Antipyrine) colorimetric method (Pars Azmoun, Tehran, Iran).
Kumar, "Synthesis and spectral studies of Cu(II) coordination compounds of 4[N-(cinnamalidene) amino] antipyrine semicarbazone," Asian Journal of Chemistry, vol.
Jawad, "Synthesis and study of Fe(III), Co(II), Ni(II) and Cu(II) complexes of new Schiff's base ligand derived from 4-amino antipyrine," Journal of Applicable Chemistry, vol.
Total cholesterol was measured by CHOD/PAP (Cholesterol oxidase/peroxidase aminoantipyrine) method in serum or plasma, whereas for the determination of triglycerides in serum or plasma G PO/PAP (Glycerol phosphate oxidase/peroxidase aminoantipyrine) method was used, (20) HDL cholesterol was estimated by PEG/CHO-DPAP(Polyethylene glycol/Cholesterol oxidaseperoxidase amino antipyrine) method.
METHODS: Thirty patients were randomly divided into two groups, matched with respect to clinical features, impairment of hepatic function (as judged by liver function tests including antipyrine elimination) and immunosuppression (phagocytic and killing capacities of neutrophils).
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