antisense strand


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Related to antisense strand: minus strand, plus strand

antisense strand

[¦an·tē′sens ‚strand]
(cell and molecular biology)
The strand of a double-stranded deoxyribonucleic acid molecule from which ribonucleic acid is transcribed. Also known as anticoding strand.
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References in periodicals archive ?
Since there were not enough students, the sense strand moved away, but the students were told that the opening of the helix and transcription actually occur simultaneously The sense-strand students exchanged their DNA codes for mRNA codons and moved back in line, one by one, to face the antisense strand, demonstrating that the antisense strand was the template for transcription.
The filter for the [DELTA]G (free energy) at the 5'-end of the antisense strand (f-dga).
Asymmetric amplification of the antisense strand occurred in 10 [micro]L of 50 mmol/L Tris, pH 8.
The resulting primary RNA strand is complementary to the DNA antisense strand and is identical to the nucleotide sequence expressed by the sense DNA strand, except that the nucleotide uridine (U) replaces T during complementary base pairing (A-U in RNA, A-T in DNA) [ILLUSTRATION FOR FIGURE 2 OMITTED].
an asymmetrical chemical modification design, where the modification in the sense strand cannot be used in the antisense strand.
The silencing potency and specificity of the antisense strand, however, is fully maintained.
For the sense strand (FAM), the peaks were defined by the following data points: wild-type 1, 5756; wild-type 2, 5809; mutant 1, 5736; mutant 2, 5788, and for the antisense strand (HEX): wild-type, 5867; mutant, 5738.
Chimeric RNA-DNA duplexes (Patent Pending): These novel RNAi-like compounds, comprised of a RNA antisense strand and a modified DNA sense strand, were designed to provide potential specificity advantages compared with first generation siRNA.
The first product, now on the market, amplifies the antisense strand of RNA.