Also found in: Dictionary, Thesaurus, Medical, Legal.



a procedure for the chemical and biological disinfection of wounds, objects touching them, the operative field, and the surgeon’s hands and for the counteraction of infection in the patient’s organism. In surgery, antisepsis is used only in combination with asepsis. Antisepsis as a method of preventing microbes from penetrating a wound was first proposed in 1867 by the English surgeon J. Lister. The method consisted of applying to the wound a multi-layered hermetic dressing saturated with carbolic acid, spraying carbolic acid into the air of the operating room, smearing the operative field with it, and treating the surgeon’s hands, instruments, sutures, and gauze with it. The acute toxic effect of carbolic acid on the wound, on the patient’s organism, and on those nearby very quickly forced them to give up this method. The science of antisepsis continued to develop as more effective but less toxic antiseptic agents (antiseptics) appeared possessing bactericidal and bacteriostatic properties that activate the organism’s defense forces, increase phagocytosis, have no harmful effects on the organism, and do not lose their effectiveness upon contact with pus. Antibiotics most fully meet these requirements. Preparations derived from sulfanilamides—Prontalbin, “sulfazol,” “sulfodimezin,” “aethazol,” and others—which are used predominantly in streptococcus, pneumococcus, and meningococcus infections, also possess antiseptic properties. The phytoncids contained in a number of plants—garlic, onion, European bird cherry, black currant, citrus and coniferous trees, and others—possess good antibacterial properties.


Mnogotomnoe rukovodstvo po khirurgii, vol. 1. Moscow, 1962.


References in periodicals archive ?
Once in the operative theater, two more additional steps were taken to maintain antisepsis.
For now, "we believe that future guidelines should specify the choice of antisepsis prior to abdominal hysterectomy," he said at the meeting, which is jointly sponsored by the American College of Surgeons.
The main findings of our audit related to poor compliance with hand hygiene practices, lack of use of sterile gloves and inadequate skin and bottle-top antisepsis.
However, it was not until the late 1860s after Joseph Lister introduced the principles of antisepsis that post-operative infections decreased substantially.
It incorporates tables, illustrations, clinical cases, and study questions, and introduces microbiology, commensal and pathogenic microbial flora in humans, and sterilization, disinfection, and antisepsis, as well as the techniques used by microbiologists and immunologists, then covers immunology (updated and reorganized for this edition), including cells and tissues, innate immunity, antigen-specific immunity, antimicrobial immunity, and vaccines, and bacteria, viruses, fungi, and parasites.
Natural carbon dioxide gas (co2) coming from the principal hot spring of royat (france) and is used for four qualities: vasodilatation, antalgy, healing and antisepsis properties.
The removal of wristwatches, bracelets and other jewellery is generally advised for all clinical hand hygiene episodes--not only for surgical antisepsis.
The third product is Sage 2% Chlorhexidine Gluconate Cloths -- Patient Preoperative Skin Preparation, which contains 500mg of rinse-free 2% CHG solution per cloth for rapid, broad spectrum skin antisepsis with persistent activity.
The purpose of preoperative skin antisepsis is to remove soil, transient and resident microorganisms from the skin surface, and to prevent wound contamination on incision (Edwards et al 2004, AORN 2008, Veiga et al 2008, Hemani & Lepor 2009).
Joseph Lister revolutionized surgery with carbolic acid antisepsis.
Many interventions that have contributed to decreases in bloodstream infections in ICUs have targeted catheter insertion, including the use of maximal barrier precautions (such as a gown, mask, cap, sterile gloves, and a full body drape) at insertion and the use of chlorhexidine for skin antisepsis (CDC, 2011a).