Antisepsis


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Antisepsis

 

a procedure for the chemical and biological disinfection of wounds, objects touching them, the operative field, and the surgeon’s hands and for the counteraction of infection in the patient’s organism. In surgery, antisepsis is used only in combination with asepsis. Antisepsis as a method of preventing microbes from penetrating a wound was first proposed in 1867 by the English surgeon J. Lister. The method consisted of applying to the wound a multi-layered hermetic dressing saturated with carbolic acid, spraying carbolic acid into the air of the operating room, smearing the operative field with it, and treating the surgeon’s hands, instruments, sutures, and gauze with it. The acute toxic effect of carbolic acid on the wound, on the patient’s organism, and on those nearby very quickly forced them to give up this method. The science of antisepsis continued to develop as more effective but less toxic antiseptic agents (antiseptics) appeared possessing bactericidal and bacteriostatic properties that activate the organism’s defense forces, increase phagocytosis, have no harmful effects on the organism, and do not lose their effectiveness upon contact with pus. Antibiotics most fully meet these requirements. Preparations derived from sulfanilamides—Prontalbin, “sulfazol,” “sulfodimezin,” “aethazol,” and others—which are used predominantly in streptococcus, pneumococcus, and meningococcus infections, also possess antiseptic properties. The phytoncids contained in a number of plants—garlic, onion, European bird cherry, black currant, citrus and coniferous trees, and others—possess good antibacterial properties.

REFERENCE

Mnogotomnoe rukovodstvo po khirurgii, vol. 1. Moscow, 1962.

A. B. GALITSKII

References in periodicals archive ?
Other pre-analytical factors that may also have played a role in the high BC contamination rate but were not explored in our study include whether or not the venepuncture site was repalpated after skin antisepsis, patient-related factors (e.
APIC guideline for handwashing and hand antisepsis in health care settings.
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Key Words: antisepsis, civil rights, gynecology, history of medicine, medical ethics, women's rights
Whole chapters are devoted to Alexander Gordon, who is credited with being the first person to fully appreciate the fact that puerperal fever could be conveyed from patient to patient on the hands of the midwife or surgeon, to Ignaz Semmelweis, who is said to have been the first individual to insist that all practitioners must wash their hands before having contact with women in childbed, and Joseph Lister, who first introduced antisepsis into surgical practice.
SAN DIEGO -- Use of the antisepsis agent, activated protein C, is not associated with late excess mortality in patients who are treated and survive what otherwise might be fatal sepsis, Dr.
The surgical suites at Columbia University and at Cornell University, both in New York, are switching to alcohol-based antisepsis, she said at the meeting sponsored by the American Society for Microbiology.
British journal The Lancet accepted Lister's article on the prevention of infections and the era of antisepsis was under way.
It is sobering to think that we still use a neurosurgical procedure begun 10,000 years ago, before antisepsis or anesthesia.
The main scientific and medical changes which occurred were in the fields of anaesthesia, antisepsis and asepsis, microbiology and radiography - all areas which today form the basic foundations of modern health care.
Her Clepsydra, 2000, a bottle suspended mouth down from a stainless-steel brace, drips an indigo solution onto the fl oor, as if to inaugurate a ceremony fusing western antisepsis and African ritual.
The development of anesthesia in the 1840s and antisepsis in the 1860s changed the hospital from a largely custodial institution to a preferred site of operations for surgical cures and relief.