antithrombin


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Related to antithrombin: heparin, Antithrombin deficiency

antithrombin

[‚an·tē′thräm·bən]
(biochemistry)
A substance in blood plasma that inactivates thrombin.
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References in periodicals archive ?
Name the antithrombin heparin binding site methods that have been used.
2012) Thrombosis from a prothrombin mutation conveying antithrombin resistance.
20,21 Saray A et al in 2012 has shown that in chronic hepatitis the level of antithrombin is reduced and may be used as an early marker of hepatocellular damage.
Normally the natural inhibitors of coagulation like Protein C (PC) Protein S (PS) antithrombin III (AT III) inhibit the coagulation factors activated during process of haemostasis.
The antithrombin levels in the 2 populations are given in Table 2.
Cox notes that ATryn was developed to provide a safe and consistent supply of recombinant antithrombin.
When a woman has a deficiency other than protein S, protein C, or antithrombin, these findings may not be valid.
The new product, which is a human antithrombin III concentrate, is indicated for the treatment of thrombosis associated with congenital antithrombin III deficiency as well as disseminated intravascular coagulation.
During warfarin anticoagulation, a hematologic evaluation yielded normal values for antithrombin III, lupus anticoagulants, prothrombin gene mutations, antinuclear antibodies, and anticardiolipin antibodies.
The model was applied to the test results for plasma antithrombin activity, a routine assay frequently used in the hemostasis laboratory, over the period 1996-1999.
The list of causative factors for hypercoagulability, defined as a predisposition to thrombosis within the flowing blood of the affected person, is lengthy and includes alterations in antithrombin, protein C and S, homocysteine, prothrombin, and hereditary factors.
At 2 years antithrombin III levels declined by 10% among women in the tamoxifen group, compared with women taking placebo, reported Dr.