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any of a group of antibodies formed in the body as a response to the introduction of poisonous products, or toxinstoxin,
poison produced by living organisms. Toxins are classified as either exotoxins or endotoxins. Exotoxins are a diverse group of soluble proteins released into the surrounding tissue by living bacterial cells. Exotoxins have specific reaction sites in the host; e.g.
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. By introducing small amounts of a specific toxin into the healthy body, it is possible to stimulate the production of antitoxin so that the body's defenses are already established against invasion by the bacteria or other organisms that produce the toxin. See immunityimmunity,
ability of an organism to resist disease by identifying and destroying foreign substances or organisms. Although all animals have some immune capabilities, little is known about nonmammalian immunity.
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An antibody that will combine with and generally neutralize a particular toxin. When the manifestations of a disease are caused primarily by a microbial toxin, the corresponding antitoxin, if available in time, may have a pronounced prophylactic or curative effect. Apart from this, the other properties of an antitoxin are those of the antibody family (lgG, IgA, IgM) to which it belongs. See Antibody, Biologicals, Immunoglobulin

Antitoxins have been developed for nearly all microbial toxins. Diphtheria, tetanus, botulinus, gas gangrene, and scarlatinal toxins are important examples. Antitoxins may be formed in humans as a result of the disease or the carrier state, or following vaccination with toxoids, and these may confer active immunity. The status of this can be evaluated through skin tests, or by titration of the serum antitoxin level. See Botulism, Diphtheria, Immunity, Toxin-antitoxin reaction

McGraw-Hill Concise Encyclopedia of Bioscience. © 2002 by The McGraw-Hill Companies, Inc.


An antibody elaborated by the body in response to a bacterial toxin that will combine with and generally neutralize the toxin.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.


1. an antibody that neutralizes a toxin
2. blood serum that contains a specific antibody
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005
References in periodicals archive ?
As the man responsible for implementing the state's tough antitoxic law, the tone of his article should give national packers reason to relax.
PCs possess a variety of biological activities, including antioxidant, antitumor, anti-inflammatory, antiallergic, and antitoxic effects [17].
This plant has several advantages including antimicrobial, antibacterial, antioxidant and antitoxic activities used in the treatment of cardiovascular diseases, diabetes, tumors, articular pains and respiratory diseases (Abbas et al., 2010).
antitoxic, and nephroprotective effect Cadmium-induced 10 [micro]M final Antioxidant potential kidney cone, to the isolated mitochondrial mitochondria injury Acetylsalicylic 20 [micro]g/kg/day, Reduces the concentration acid toxicity p.o.
Among these three studied inhibitors, the suppressor of the NF-[kappa]B cascade, IKK Inhibitor XII, has been shown to be the most effective antitoxic agent in vitro [5].
Vitis species, from the family Vitaceae, have been traditionally used world-wide as medicinal herbs with anti-inflammatory, analgesic, and antitoxic properties (Nassiri-Asl and Hosseinzadeh, 2009).
Three momarsa for the supply of (a) detergents, (b) antibiotics (antitoxic), also (c) fourth ammonium chloride.
To evaluate the possible protective roles of antibacterial and antitoxic immunities in cholera we made use of the elegant rabbit ileal loop technique developed by De (2) and modified the assay slightly to allow determination of the protective efficacy of different cholera antigens (3).
The skin-visceral cases require hospitalization for proper antishock and antitoxic management, carrying out the rigorous handling of fluids and electrolytes, with an indication of blood transfusion when necessary [5,9].
This subtle genetic change might also alter the effectiveness of current cholera vaccines which stimulate antitoxic as well as antibacterial immunity.