An official at PIMS pharmacy who did not want to be named said the hospital was running out of anti-rabies and antivenin
drugs and permission to allow life-saving drugs' import will greatly benefit patients.
So far we have registered two antivenins
which are very effective," noted Dr Matendechero.
Retrospection and prospection for manufacturing of snake antivenins
It should be considered that antivenin
treatment can be more hazardous than the snake poison itself (8).
The treatment of black widow spider envenomation involves local wound care, symptomatic treatment that includes benzodiazepine and opioids, and the delivery of the toxin's antidote antivenin
to patients that present with systemic findings (8).
He had been treated with 26 doses of antivenin
. Doctors told her a normal bite is usually treated with two to four doses.
was purchased from Shanghai Biotechnology Co.
Using monovalent antivenin
is preferred as it is more efficacious and cost effective and has less risk of adverse reactions due to the smaller volume required for treatment as compared to polyvalent.
One vial of reconstituted antivenin
was given via intravenous route followed by another vial mixed with normal saline via constant rate infusion over a period of one hour.
The patient was thus able to provide the first responders with detailed information about the snake and on where to obtain the corresponding antivenin
. He instructed his wife to apply a pressure bandage to the forearm.
Two days after receiving the antivenin
, he developed disturbance in the level of consciousness, respiratory distress, and coagulopathy; a brain CT with IV contrast revealed bilateral hypodensities that resolved upon resolution of the symptoms .
is the only specific treatment towards envenomation.