crisis

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Related to aplastic crisis: aplastic anemia, sequestration crisis

crisis

Pathol a sudden change, for better or worse, in the course of a disease

Crisis

 

a sharp turning point in the course of a disease that is accompanied by a drop in elevated body temperature and improvement in the patient’s condition.

A crisis usually occurs in acute-onset diseases with a rapid rise in temperature (croupous inflammation of the lungs, malaria, relapsing fever, and so forth). A crisis is associated with profuse sweating, marked weakness, and sometimes a temporary slowing of cardiac activity. A crisis is the opposite of a gradual subsidence of a pathological process and lowering in temperature called lysis. A crisis is to be distinguished from a pseudocrisis, in which there is only a temporary lowering of temperature and improvement in the patient’s condition. A critical drop in temperature may also occur as a result of removal of the suppurative focus from the patient’s body or administration of powerful antimicrobial agents.

crisis

[′krī·səs]
(medicine)
The turning point in the course of a disease.
(psychology)
The psychological events associated with a specific stage of life, as an identity crisis or developmental crisis.
References in periodicals archive ?
Aplastic crisis in sickle cell anemia; a study of its mechanism and its relationship to other types of hemolytic crises.
In the present study, we described a family with HS that all three members developed aplastic crisis secondary to HPV B19 infection leading to the detection of asymptomatic HS.
One of the theories behind the etiology of transient pancytopenia in HPV B19 infections is that the virus could be responsible for the temporary arrest of hematopoiesis that leads to aplastic crisis in persons with chronic hemolytic anemia.
HPV B19 induced aplastic crisis in a family leading to the diagnosis of hereditary HS is a very rare reported event in the literature.
In sickle cell anemia, erythrocyte membrane defects, red cell enzyme defects, thalassemia, and acquired hemolytic anemia result in stressed erythrocyte production as in hemorrhage, iron deficiency anemia and bone marrow transplantation, in which there may be a red cell hemolytic process, and the preceding PV infection can present with transient aplastic crisis (38), (39), (47).
In patients with hemolytic anemia, bone marrow examination is not required to establish the diagnosis of aplastic crisis.
Therefore, the patients who are capable of the transmission of parvovirus B19 are not just those with erythema infectiosum, but include children with hematologic disorders, aplastic crisis, and immunocompromised patients with chronic aplastic anemia.
Children hospitalized with an aplastic crisis are highly contagious, and respiratory control measures should be instituted to reduce transmission.