apob

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apob

[′ā‚päb]
(meteorology)
An observation of pressure, temperature, and relative humidity taken aloft by means of an aerometeorograph; a type of aircraft sounding.
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LDLs containing only apoB-100 were shown to bind to cell-surface receptors on fibroblasts, known as the LDL receptor (LDLR) (11).
It reduces the rate of apoB-100 synthesis, thereby reducing the VLDL concentration which is risk factor for atherosclerosis.
Huff, "The molecular mechanisms underlying the reduction of LDL apoB-100 by ezetimibe plus simvastatin," Journal of Lipid Research, vol.
There are two forms of the ApoB protein, apoB-100 and apoB-48, resulting from tissue-specific alternative splicing.
ApoB gene expresses in two isoforms as ApoB-48 in chylomicron and ApoB-100 in the liver.
They include LDL ("bad") cholesterol that can clog arteries, HDL ("good") cholesterol that can help remove LDL molecules, and triglycerides, as well as ApoB-100, Lp-PLA-2 and others.
Due to the extremely cationic character, MPO can easily bind to the negatively charged structures, that is, bacteria, endothelial cells, cytokeratin-1, polyanionic matrix glycosaminoglycans, apolipoproteins apoA-1 and apoB-100, ceruloplasmin, [alpha]1-antitrypsin, and albumin [21].
(18) As a consequence, insulin inhibits hepatic secretion of VLDL-TG and apoB-100.
Supplemented patients also had a significant decline in concentrations of apolipoprotein B-100 (apoB-100), a marker of LDL particle number and a known risk factor for cardiovascular disease.