As stated above, reference to apocrine gland
It can be seen as an ectopic tumor developing from heterotopic apocrine glands
in head and neck, external ear (ceruminus gland), palpebral (Moll's gland), breast, cheek, eyebrow, trunk, nose and limb.
The etiology of hidradenitis suppurativa is unknown but appears to involve bacterial infection in the apocrine glands
and starts as a single inflamed follicle that spreads secondarily through the sinus tracts.
(5,6) This epithelial transition mirrors the physiologic epithelial transition of the apocrine gland
to the follicular infundibulum (Figure 4).
carcinoma of the axilla: review of the literature and recommendations for treatment.
Some cases of nevus sebaceus also possess apocrine glands
(or eccrine glands with apocrine features).
Misago and Narisawa hypothesized the reason to be special structures of skin in these areas such as abundant apocrine glands
and subcutaneous tissue. As in our case, the lesion was found on the right groin, also a nonsun-exposed region.
By contrast, apocrine glands
occur in areas that contain a lot of hair follicles, like the groin and armpit.
Hair follicles and glands with ducts can also be found in this skin layer, along with sweat glands, apocrine glands
, and sebaceous glands.
HS is a chronic, inflammatory skin disorder that causes abscesses and scarring on the skin, affecting areas rich in apocrine glands
such as the armpits, breasts and groin.
Vascular alterations are due to distension, instability, and proliferation of vessels leading to spider angiomas, palmar erythema, varicosities, and gingival edema.7 Similarly, glandular activity may also be altered.10 Secretions of sebaceous and eccrine glands is increased while that of apocrine glands
is decreased.7 The underlying mechanisms of most cutaneous changes of pregnancy include increased activity of the maternal adrenal and pituitary glands along with a contribution from the developing fetal endocrine glands, increased cortisone levels, accelerated metabolism, and enhanced production of progesterone and estrogen hormones.11
"It has a high affinity for adipose tissue, and we believe that its targeted effect at the level of the eccrine and apocrine glands
should help improve hyperhidrosis.