nanoparticles for efficient drug delivery to tumors," ACS Nano, vol.
TEHRAN (FNA)- Iranian researchers applied apoferritin
protein cage to synthesize cobalt nanoparticles for designing an appropriate biosensor to detect various compounds, including hydrogen peroxide, phenol, etc.
Ferritin that is not associated with iron is called apoferritin
and subunit combination varies in different tissues (5).
It is composed of spherical outer shell of an iron-free protein, apoferritin
, andan inner core of trivalent iron Fe+3 (oxidized)1.
In the intestinal mucosal cell, ferrous iron is bound by apoferritin
and then oxidized by ceruloplasmin to ferric iron bound to ferritin.
When infection or inflammation is present, neutrophils release lactoferrin or apoferritin
Vekilov and Siu-Tung Yau at the University of Alabama in Huntsville used an atomic force microscope to view the protein apoferritin
as it crystallizes.