apob

(redirected from apolipoprotein B-100)
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apob

[′ā‚päb]
(meteorology)
An observation of pressure, temperature, and relative humidity taken aloft by means of an aerometeorograph; a type of aircraft sounding.
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References in periodicals archive ?
mipomersen sodium) Injection 200 mg/mL KYNAMRO is an oligonucleotide inhibitor of apolipoprotein B-100 synthesis indicated as an adjunct to lipid-lowering medications and diet to reduce low density lipoprotein-cholesterol (LDL-C), apolipoprotein B (apo B), total cholesterol (TC), and non-high density lipoprotein-cholesterol (non-HDL-C) in patients with homozygous familial hypercholesterolemia (HoFH).
Isis Reports Positive Data from KYNAMRO (mipomersen sodium) FOCUS FH Phase 3 Study in Patients with Severe Heterozygous Familial Hypercholesterolemia
VLDL is assembled on apolipoprotein B-100 (apoB100) and comprises 50% TG, 20% cholesterol esters, 15% phospholipids and 15% protein.
The influence of glucocorticoids on lipid and lipoprotein metabolism and atherosclerosis
LDL contains a core of hydrophobic lipid, mostly cholesteryl ester, a shell of phospholipids, and single molecule of the large protein apolipoprotein B-100 (apo B).
Beyond LDL cholesterol in assessing cardiovascular risk: apo B or LDL-P?
We investigated the potential role and mechanism of action of an indole-based compound, indole-3-carbinol (I3C), on apolipoprotein B-100 (apoB) production using HepG2 cells.
Cruciferous indole-3-carbinol inhibits apolipoprotein b secretion in HepG2 cells
7 Total cholesterol, mg/dl 194 [+ or -] 47 189 [+ or -] 57 LDL-cholesterol, mg/dl 125 (64-1006) 119 (61-1042) HDL-cholesterol, mg/dl 41 [+ or -] 6 41 [+ or -] 9 Triglyceride, mg/dl 132(43-331) 139 (67-466) Lipoprotein (a), mg/dl 35 (10-174) 31 (2-112) Apolipoprotein A-1, mg/dl 124 [+ or -] 27 129 [+ or -] 34 Apolipoprotein B-100, mg/dl 116(52-222) 107 (63-161) Homocysteine, [micro]mol/l 13.
The relation between coronary lesion distribution and risk factors in young adults/Genc eriskinlerde koroner lezyon dagilimi ile risk faktorlerinin iliskisi
Mipomersen, formerly ISIS 301012, is a lipid-lowering drug targeting apolipoprotein B-100.
Genzyme and Isis Form Alliance for High Risk Cardiovascular Patients
The analysis also showed that the ratio of total cholesterol to HDL cholesterol was at least as good for predicting the risk of the ocurrence of cardiovascular events as was the ratio of apolipoprotein B-100 to HDL lipoprotein cholesterol (JAMA 2005;294:326-33).
C-reactive protein may alter women's Framingham risk score
There were no significant changes in serum total cholesterol, triglyceride, LDL-cholesterol, HDL-cholesterol or apolipoprotein B-100 concentrations with black tea ingestion.
Effect of black tea on the fasting concentrations of chylomicrons and chylomicron remnants in humans. (Original Research)
Familial defective apolipoprotein B-100 (FDB) and familial hypercholesterolemia (FH) are common causes of monogenic primary hypercholesterolemia.
The ubiquitous, lipids and related diseases: A laboratory perspective
Another subunit of lipoprotein(a), called apolipoprotein B-100, already has been fingered as a culprit in atherosclerosis (SN: 2/7/87, p.
Lipoprotein findings may solve one riddle ... and pose another
Isis Pharmaceutical Compound: ISIS 301012, a second-generation antisense inhibitor of apolipoprotein B-100 (ApoB), which has demonstrated potent, prolonged dose-dependant reduction of ApoB, cholesterol, low- density lipoprotein (LDL-C) and very low-density lipoprotein (VLDL) in Phase 1 trials.
Windhover Information's 2006 Therapeutic Alliance Series: Cardiovascular Conference
Complete deficiency of the low-density lipoprotein receptor is associated with increased apolipoprotein B-100 production.
Measurement of fractional synthetic rates of multiple protein analytes by triple quadrupole mass spectrometry

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