arachidonate


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Related to arachidonate: Phosphatidate

arachidonate

[‚a¦rak·ə¦dän‚āt]
(biochemistry)
A salt or ester of arachidonic acid.
References in periodicals archive ?
remodeling Production of arachidonate metabolites or PUFA- containing lysophospholipids PNPLA9 Membrane remodeling Production of AA metabolites or PAF PAF-AH PLA2G7 Hydrolysis of extracellular PAF, Degradation of oxidized phospholipids in lipoproteins PAFAH2 Degradation of oxidized phospholipids in cell membranes PAFAH1B2 Hydrolysis of intracellular PAF PAFAH1B3 Hydrolysis of intracellular PAF LPLA2 PLA2G15 Lysosomal degradation of phospholipids PLAAT PLA2G16 Production of eicosanoids?
Arachidonate acid (ARA) metabolites are important lipid mediators regulating inflammation, analgesia, angiogenesis and cell proliferation [Bogatcheva et al.
Inhibition of arachidonate 5-lipoxygenase triggers massive apoptosis in human prostate cancer cells.
peroxiredoxin (PRX), arachidonate 5-lipoxygenase, a glutathione S-transferase, and several cytochrome P450 and HSPs), cell motility (ca.
ROS can arise from: (1) The mitochondrial electron transport chain as part of oxidative phosphorylation; (2) The metabolism of arachidonate by cyclooxygenase or lipoxygenase enzymes to prostaglandins or leukotrienes; (3) Cytochrome p 450 enzymes; (4) Oxidase enzymes like NADPH oxidase and (5) The nitric oxide synthetases.
Arachidonate 12-lipoxygenase is localized in neurons, glial cells, and endothelial cells of the canine brain.
Expressions of cyclooxygenase-2 and prostaglandin E-receptors in carcinoma of the gallbladder: crucial role of arachidonate metabolism in tumor growth and progression.
Results clearly indicated that arachidonate metabolites, probably PGE2, mediated skin vasodilation during CO2-water bath.
Through inhibition of the cyclooxygenase (COX) pathway of arachidonate metabolism, NSAIDs prevent the production of the proinflammatory prostaglandins.
Inhibition of sheep platelet arachidonate metabolism by flavonoids from Spanish and Indian medicinal herbs.