arachidonic acid


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Related to arachidonic acid: arachidonic acid cascade

arachidonic acid

[ə¦rak·ə¦dan·ik ′as·əd]
(biochemistry)
C20H32O2 An essential unsaturated fatty acid that is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.
References in periodicals archive ?
Although we believe that dual inhibition is more effective on suppression of cell multiplication and stimulation of apoptotic mechanism, there are some studies indicating that blocking only one way of the arachidonic acid metabolism (COX or LOX) results in decreasing viability of cancer cells.
Most of the functions of oxylipins derived from arachidonic acid, also called eicosanoids, are well known and primarily associated with immuno-stimulatory events (which stimulate the immune system) and pro-coagulant actions (which promote blood coagulation).
A total number of 6 (25%) and 7 (29%) subjects had decreased platelet aggregation post-treatment in response to collagen and arachidonic acid agonists, respectively.
In an earlier phase of the study, he said, arachidonic acid failed to show the expected aspirin inhibition in 17 of 192 heart attack patients who had been prescribed aspirin.
Approximately 1 ml of fresh blood was taken, analysed in its original state and then activated with arachidonic acid (AA) and kaolin.
Interestingly, there are indications that the disturbances in arachidonic acid utilization for eicosanoids production and the ensuing elevation in arachidonic acid levels exert proapoptotic effects as well as affect the capacity for PAF generation.
Rather, the level of arachidonic acid is lower in the elderly male than the young female.
Role of arachidonic acid metabolism in the mitogenic response of Balb/c 3t3 fibroblasts to epidermal growth factor.
A possible mechanism for the protective effect of omega-3 supplementation is a reduction in arachidonic acid derived inflammatory mediators, such as prostaglandins and thromboxane," Dr.