arteriolopathy


Also found in: Medical.

arteriolopathy

[är‚tir·ē·ə′läp·ə·thē]
(medicine)
Disease of the arterioles.
References in periodicals archive ?
Calciphylaxis or calcific uremic arteriolopathy (CUA) is a term that refers to the deposition of calcium in small and medium vessels of the skin that can result in thrombosis and necrosis of the skin, subcutaneous fat, and muscle.
Uric acid stimulates VSMC proliferation triggers renal microvascular disease and afferent arteriolopathy leading to increased BP.
Calciphylaxis or calcifc uremic arteriolopathy is a severe complication of advanced chronic kidney disease (CKD) and other risk factors, including female gender, Caucasian race, obesity, diabetes mellitus, systemic autoimmune and liver diseases, elevated levels of calcium-phosphate product, hypercoagulable diseases, and therapy with calcium and vitamin D analogues, warfarin, corticosteroid drugs, and immunosuppressive drugs (1).
Calciphylaxis or calcific uremic arteriolopathy (CUA) is a rare and severe disorder characterized by systemic medial calcification of arteries and arterioles that leads to skin and soft tissues ischemic necrosis with the development of ulcers (1).
has completed its Phase II clinical trial of SNF472, its lead candidate for the treatment of the orphan disease calciphylaxis (calcific uraemic arteriolopathy, CUA), with both primary and secondary endpoints being successfully met, the company said.
has completed the Phase II clinical trial of SNF472, its lead candidate for the treatment of the orphan disease calciphylaxis (calcific uraemic arteriolopathy, CUA), the private company announced on Tuesday.
Mihatsch, "Studies on morphological outcome of cyclosporine associated arteriolopathy after discontinuation of cyclosporine in renal allografts," Pediatric Nephrology, vol.
The impacts of secondary hyperparathyroidism are bone resorption caused by the increased osteoclast activity, soft tissue calcification (calciphylaxis), cardiovascular events, pruritus, calcific uremic arteriolopathy, and many other [4].
Calcific uremic arteriolopathy can be characterized by obstructive vasculopathy, with calcification of small arteries and arterioles resulting in luminal occlusion and subsequently cutaneous necrosis [1].
(1) Chronic nephropathy induced by CsA is characterized by irreversible impairment of kidney function and progressive histological lesions, including tubulointerstitial fibrosis, arteriolopathy, and tubular atrophy.
Dymock et al., "Cutaneous necrosis from calcific uremic arteriolopathy," American Journal of Kidney Diseases, vol.
Khanna, "Vascular ossification--calcification in metabolic syndrome, type 2 diabetes mellitus, chronic kidney disease, and calciphylaxis--calcific uremic arteriolopathy: the emerging role of sodium thiosulfate," Cardiovascular Diabetology, vol.