ascaridole


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ascaridole

[ə′skar·ə‚dōl]
(organic chemistry)
C10H16O2 A terpene peroxide, explosive when heated; used as an initiator in polymerization.
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Two of these comprise the production of a drug: the antimalarial artimesinin and ascaridole, a defense against parasitic worms.
Particularly in Chenopodium ambrosioides the secondary metabolites included: organic acids, flavones (glycoside), flavonols and their glycosides (kaempferol, quercetin, and isorhamnetin), sterols and phytosterols (avenasterol and spinasterol), monoterpenoids (acyclic such as [beta]-myrcene, cis-[beta]-ocimene and its transisomer, nerol and geraniol, and citronellyl acetate; monocyclic such as limonene, [alpha]-terpinene and its [gamma]-isomer, [alpha]-terpinolene, [beta]-phellandrene, p-cymene, carvacrol, thymol, trans-pinocarveol and [alpha]-terpineol, carvone, pinocarvone, piperitone and its acetates, and ascaridole; and bicyclic such as chanopanone), sesquiterpenoids ([beta]-caryophyllene and [gamma]-curcumene), and carotenoids ([alpha]-carotene and [beta]-carotene) [17].
Synthesis and nematocidal activity of ascaridole derivates against Meloidogyne incognita and Aphelenchoides besseyi.
ambrosioides, que presento en esta investigacion una CDA a las 24 h de incubacion, se han reportado compuestos antihelminticos, antitripanosoma y amebicida identificados como monoterpentenos (ascaridole), ademas de aceites esenciales; por otro lado, en M.
De la misma manera, Chenopodium ambrosioides con componentes hidroalcoholicos como el ascaridole, tienen efecto antinematocida (MacDonald et al., 2004), al igual que el ajo (Allium sativum), por su contenido de allicin, del cual se han producido componentes sinteticos como el trisulfito de diallyl, que se describe tener propiedades antiparasitarias que inhiben el metabolismo de crecimiento hasta en un 50% (Lun et al., 1994).
Lamb's-quarters leaves are a source of ascaridole, an oil used to treat for round worms and hook worms.