Those cellular changes may eventually be detected during a routine pap smear and receive the diagnostics of ASCUS
A analise dos resultados obtidos com a realizacao deste estudo possibilitou as seguintes conclusoes: A prevalencia de lesoes intraepiteliais de alto grau em mulheres com diagnostico colpocitologico de atipias de significado indeterminado (ASCUS
) foi de 23,7%, se mostrando dessa forma bastante elevada quando comparada a outras cidades brasileiras (COSTA; BARROS, 2011).
The performance of MGMT and C13ORF18 methylation combined with HR-HPV detection for triage of ASCUS
and LSIL is shown in [Table 5].
If cytology testing reports ASCUS
or a more concerning result, the woman is referred for colposcopy.
Pap smear had the greatest sensitivity when ASCUS
and above lesions were considered as positive, but the specificity was at its peak when HSIL and above lesions were taken as significant.
Arrangement of ascospores in linear fashion in an ascus
and presence of mucilaginous sheath is therefore considered important morphological characters for the identification of S.
The percentage of spherical, sub-spherical and ellipsoid spores varied among the ascus
type (1-, 2-, 3-, 4-and 5-spored asci).
The woman with CIN 3 underwent a LEEP with follow-up Pap smear testing showing ASCUS
TABLE USPSTF cervical cancer screening recommendations (2) Age (years) Recommendation <21 No screening 21-29 Screen with cytology every 3 years, with reflex HPV testing if ASCUS
is detected 30-65 Screen with a combination of cytology and HPV testing every 5 years (cytology every 3 years is an acceptable option) >65 Discontinue screening ASCUS
, atypical squamous cells of undetermined significance; HPV, human papillomavirus; USPSTF, US Preventive Services Task Force.
Some ascomyceous fungi grow as single-celled yeasts, which do not form fruiting bodies as it developed into an ascus
during sexual reproduction.
: atypical squamous cells of undetermined significance; ASCH: atypical squamous cells without high/ grade lesion; LSIL/HSIL/CA: low/grade squamous intraepithelial lesion/ high-grade squamous intraepithelial lesion/cervical cancer.