aspartic acid


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aspartic acid

(əspär`tĭk), organic compound, one of the 20 amino acidsamino acid
, any one of a class of simple organic compounds containing carbon, hydrogen, oxygen, nitrogen, and in certain cases sulfur. These compounds are the building blocks of proteins.
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 commonly found in animal proteins. Only the l-stereoisomer participates in the biosynthesis of proteins. Its acidic side chain adds a negative charge and hence a greater degree of water-solubility to proteins in neutral solution and has been shown to be near the active sites of some enzymes (see pepsinpepsin,
enzyme produced in the mucosal lining of the stomach that acts to degrade protein. Pepsin is one of three principal protein-degrading, or proteolytic, enzymes in the digestive system, the other two being chymotrypsin and trypsin.
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). Aspartic acid is not essential to the human diet. It was discovered in protein in 1868.

aspartic acid

[ə′spärd·ik ′as·əd]
(biochemistry)
C4H7NO4 A nonessential, crystalline dicarboxylic amino acid found in plants and animals, especially in molasses from young sugarcane and sugarbeet.
References in periodicals archive ?
Aspartic acid, glutamic acid, glycine, and [beta]-alanine levels fell by 72.0%, 68.6%, 34.6%, and 31.9%.
In the much-publicized case of a dinosaur from Utah, they found that D-enantiomers in aspartic acid had reached 21 percent, casting further doubt on the authenticity of DNA from this sample (SN: 12/2/95, p.373).
As shown in Table 3, following storage at -20[degrees]C for 2 weeks, concentration of four amino acids were significantly decreased compare to R0 min: phosphoserine, aspartic acid, a-amino adipic acid, and alanine.
Trucco looks at a portion of the gene that codes for aspartic acid. People who have a specific alteration of the gene, he says, are 107 times more likely than others to develop Type I diabetes.
Same pattern was observed with aspartic acid and lysine.
In p.D514V, a polar negative amino acid aspartic acid has been substituted to a nonpolar aliphatic amino acid valine which disrupted the normal function of cGMP-binding site of CNGA3 polypeptide produced from one allele of the CNGA3 gene.26 This further strengthens the importance of aspartic acid at 514 position of CNGA3 protein.
We prepared ten kinds of metabolites, which are pyruvic acid; glucose-6-phosphate dipotassium salt; fructose-6-phosphate dipotassium salt; succinic acid; aspartic acid; isocitric acid trisodium salt; citric acid; glutamate acid; [alpha]-ketoglutarate acid; fumaric acid acid respectively.
Approximately 200 g samples of each organic growing medium amendment (i.e., seafood waste compost (SFWC), municipal solid waste compost (MSWC), and vermicompost (VC) was sent to Covance Laboratories (Madison, Wisconsin, USA) for analyses of 17 amino acids (i.e., aspartic acid, threonine, serine, glutamic acid, proline, glycine, alanine, valine, isoleucine, leucine, tyrosine, phenylalanine, lysine, histidine, arginine, cysteine, and methionine).
The first group consisted of seven amino acids (glycine, ornithine, alanine, leucine/isoleucine, tyrosine, aspartic acid, and glutamic acid) that drop sharply from the zerotime point collected shortly after birth to the median of the 6-12 month age group.
Aspartic proteinases (EC 3.4.23) or aspartyl proteinases are endopeptidases having two aspartic acid residues (Asp32 and Asp215, pepsin numbering) within their active site that are vital for their catalytic activity [7].
Tseng et al [23] classified free amino acids in food as being related to umami (aspartic acid, glutamic acid), sweet (serine, glycine, threonine, alanine), bitter (valine, methionine, isoleucine, leucine, phenylalanine, histidine, arginine), and other tastes (glutamine, tyrosine, lysine, and proline).
In fish protein hydrolysates, the amino acids found in greater quantities are aspartic acid and glutamic acid (Klompong et al., 2009, Yin et al., 2010, Ghassem et al., 2014, Hou, Li, & Zhao, 2011).