A zinc proteinase member of the astacin
family was identified in P.
Sterchi EE, Stocker W, Bond JS (2008) Meprins, membrane-bound and secreted astacin
1999) established that myosinases occurred in nonmuscle tissues, and they identified a new form (myosinase III) that had sequence homology to the astacin
group of zinc-dependent endopeptidases (Titani et al.
A developmental^ regulated metalloproteasa secreted by host-stimulated Ancylostoma caninum third- stage infective larvae is a member of the astacin
family of proteases.
Identification and characterization of hydra metalloproteinase 2 (HMP2): a meprin-like astacin
metalloproteinase that functions in foot morphogenesis.
Interestingly, one of the VEB genes, SPAN, encodes a member of the astacin
The matrix metalloproteinases or matrixins (MMPs) are members of the large metzincin superfamily such as the astacins
, serralysins, reprolysins, and adamalysins or disintegrin metalloproteinases (ADAMs).
, serralysins, snake venom and matrix metalloproteinases exhibit identical zinc-binding environments (HEXXHXXGXXH and Met-turn) and topologies and should be grouped into a common family, the 'metzincins'.