asthma

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asthma

(ăz`mə, ăs`–), chronic inflammatory respiratory disease characterized by periodic attacks of wheezing, shortness of breath, and a tight feeling in the chest. A cough producing sticky mucus is symptomatic. The symptoms often appear to be caused by the body's reaction to a trigger such as an allergen (commonly pollen, house dust, animal dander: see allergyallergy,
hypersensitive reaction of the body tissues of certain individuals to certain substances that, in similar amounts and circumstances, are innocuous to other persons. Allergens, or allergy-causing substances, can be airborne substances (e.g.
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), certain drugs, an irritant (such as cigarette smoke or workplace chemicals), exercise, or emotional stress. These triggers can cause the asthmatic's lungslungs,
elastic organs used for breathing in vertebrate animals, excluding most fish, which use gills, and a few amphibian species that respire through the skin. The word is sometimes applied to the respiratory apparatus of lower animals.
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 to release chemicals that create inflammation of the bronchial lining, constriction, and bronchial spasms. If the effect on the bronchi becomes severe enough to impede exhalation, carbon dioxide can build up in the lungs and lead to unconsciousness and death. Following a steady 30-year decline, asthma deaths in the United States, especially among poor, inner-city blacks and among the elderly, began to rise from the late 1970s through the early 1990s. At the same time, the incidence of asthma also increased, both nationally and worldwide.

There is no cure for asthma. Although the disease may go through a period of quiescence, it appears that childhood asthmatics do not outgrow the disease as previously believed. Treatment includes inhaled or oral steroids or bronchodilators (albuterol, theophylline), breathing exercises, and, if possible, the identification and avoidance of triggers.

asthma

[′az·mə]
(medicine)
A pulmonary disease marked by labored breathing, wheezing, and coughing; cause may be emotional stress, chemical irritation, or exposure to an allergen.

asthma

a respiratory disorder, often of allergic origin, characterized by difficulty in breathing, wheezing, and a sense of constriction in the chest
References in periodicals archive ?
Mrs Grace Adekoya, an assistant director, public health nursing officer at UCH, Ibadan stressed the need to keep substances with a strong smell like detergents away from the living area to prevent asthmatic attacks.
Asthmatic children and their caregivers who fulfilled the eligibility criteria were included.
The severity of situation can be imagined by the death rate of asthmatic patients during and after intense exacerbation of asthmatic attacks which were preventable up to some extent, but ended up with lack of immediate provision of emergency medical care.
In our previous study, we found that asthmatic patients with rs37973 mutant genotype had diminished ICS response and less improvement in GLCCI1 expression.[16] However, the association between GLCCI1 expression and the response of ICS is only a statistical speculation.
Dr Javed said that the children whose diets were low in vegetables and vitamin E were two to three times more likely to develop asthmatic symptoms than other children irrespective of other factors such as family size, affluence and parental smoking.
Experimental animals were randomly divided into two groups: normal control and asthmatic model, with 6 mice in each group.
Reduce exposure to common allergens during the sandstorms that may provoke asthmatic attacks.
Airway remodeling in asthma is closely associated with persistent and severe asthmatic symptoms and airway hyperresponsiveness.
We have recently demonstrated that volume changes of severe asthmatic lungs are preferentially smaller near basal regions and the smaller volume changes are compensated with air-volume change in apical regions [12].
In addition, IL-4 and IL-13 can stimulate mucus hyperproduction in tracheal epithelial cells, which would obstruct the airway in asthmatic patients [7].
Consistent with the previous studies, the percentage of Treg cells in the asthmatic group was lower than that in healthy group ((7.24 [+ or -] 2.49)% versus (11.13 [+ or -] 1.82)%, p < 0.01, Figures 1(a) and 1(b)).
HYDERABAD -- The increasing air pollution and dust put the number of allergic asthmatic patients high in urban populace of Hyderabad and there is the need of formation of effective strategy to control air pollution.