Toca 511 & Toca FC is an immuno-oncology therapy that will advance into a registrational trial this year in patients with recurrent glioblastoma or anaplastic astrocytoma
Low-grade neoplasms, such as meningioma and pilocytic astrocytoma
, may also exhibit this type of spread, but at a slower rate of growth than most malignant tumors.
A registrational trial, called Toca 5, will evaluate lead therapeutic candidate Toca 511 & Toca FC in patients with recurrent glioblastoma or anaplastic astrocytoma
and begin enrolling subjects in 2015.
Given the epithelial nature of the current lesion, multiple entities are eliminated, including melanoma, melanocytoma, pigmented astrocytoma
, and subependymoma.
GlobalData's clinical trial report, Anaplastic Astrocytoma
Global Clinical Trials Review, H1, 2012" provides data on the Anaplastic Astrocytoma
clinical trial scenario.
Microscopic examination revealed a grade II astrocytoma
with infiltration of the cerebral cortex (Figure, E).
- Pipeline Review, H2 2011', provides an overview of the Astrocytoma
In addition, Tocagen announced the company held a meeting with FDA and continues to advance towards initiation of a pivotal, randomized, controlled Phase 2/3 trial of Toca 511 & Toca FC in patients with recurrent glioblastoma and recurrent anaplastic astrocytoma
Scans showed he had a tumour called an astrocytoma
which will be treated with radiotherapy.
One case each of pigmented ganglioglioma,16 pilocytic astrocytoma
, and pleomorphic xanthoastrocytoma have been reported to date.
com/research/c1a911/anaplastic_astrocy) has announced the addition of Global Markets Direct's new report "Anaplastic Astrocytoma
- Pipeline Review, Q3 2011" to their offering.
1-5] The most recent World Health Organization (WHO) classification (1993) separates astrocytic tumors into 2 main groups: the diffuse astrocytomas
(WHO grades 2-4) and "other astrocytomas
," the latter comprising a number of fairly distinct clinicopathologic entities, of which pilocytic astrocytoma
is by far the most common.