There is a greater association of the development of infarcts, blood clots, hematomas, atherosis
, and a lower placental weight and volume with hypertensive syndromes (Artico et al.).
Comparison of the other variables (atherosis
, necrosis, abruptio, edema, hemorrhage, thrombus, calcifications, fibrinoid deposits, syncytial nodes, villi/field, capillaries/villus, number of hemozoins per field, immune cells in decidua, cells in apoptosis, and expression of FAS, FASL, COX-1, HIF, VEGF, and cytokines IL-2, IL-4, IL-10, IFN-g, TNF, and TGF-b in placental blood and IL-2, IL-10, and TGF-b in maternal blood) was not statistically different according to the species of infection.
Apart from this, in three biopsies, there were acute atherosis
, in another one there was increased extravillous trophoblasts, and in another one there were both acute atherosis
and increased extravillous trophoblasts (Figures 1, 2, and 3).
"In a way, if you think of the disease at an older age as atherosclerosis, at a young age it is still atherosis
. You can get the fat out of the vessel wall.
Placental findings also include fibrinoid necrosis, atherosis
of decidual vessels, and intimal thickening.
The elements include acute atherosis
(Figure 13), fibrinoid necrosis with or without foam cells (Figure 14), mural hypertrophy (Figure 15), chronic perivasculitis (Figure 15, A), absence of spiral artery remodeling (Figure 16), arterial thrombosis (Figure 17), and persistence of intramural endovascular trophoblast in the third trimester (Figure 18).
The characteristic lesions are vascular lesion which atherosis
of decidual spiral arteries, thrombosis, infarction and retro placental hematoma.
Brosens, "The ultra structure of acute atherosis
in hypertensive pregnancy," The American Journal of Obstetrics and Gynecology, vol.
(%) Normoblastemia of fetal blood 63 (19.2) Villous infarction (>5% of placental parenchyma) 38 (11.6) Hypertrophic decidual arteriolopathy 57 (17.4) Atherosis
of spiral arterioles 15 (4.6) Laminar necrosis of membranes (c) 38 (11.6) Chorionic disc microscopic chorionic pseudocysts (d) 21 (6.4) Maternal floor multinucleate trophoblastic giant cells 31 (9.4) Excessive amount of extravillous trophoblasts in chorionic disc 16 (4.9) Choriodecidual hemosiderosis 13 (4.0) Lesions related to decreased/ absent fetal blood flow, No.