asthma

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Related to atopic asthma: atopic dermatitis, intrinsic asthma

asthma

(ăz`mə, ăs`–), chronic inflammatory respiratory disease characterized by periodic attacks of wheezing, shortness of breath, and a tight feeling in the chest. A cough producing sticky mucus is symptomatic. The symptoms often appear to be caused by the body's reaction to a trigger such as an allergen (commonly pollen, house dust, animal dander: see allergyallergy,
hypersensitive reaction of the body tissues of certain individuals to certain substances that, in similar amounts and circumstances, are innocuous to other persons. Allergens, or allergy-causing substances, can be airborne substances (e.g.
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), certain drugs, an irritant (such as cigarette smoke or workplace chemicals), exercise, or emotional stress. These triggers can cause the asthmatic's lungslungs,
elastic organs used for breathing in vertebrate animals, excluding most fish, which use gills, and a few amphibian species that respire through the skin. The word is sometimes applied to the respiratory apparatus of lower animals.
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 to release chemicals that create inflammation of the bronchial lining, constriction, and bronchial spasms. If the effect on the bronchi becomes severe enough to impede exhalation, carbon dioxide can build up in the lungs and lead to unconsciousness and death. Following a steady 30-year decline, asthma deaths in the United States, especially among poor, inner-city blacks and among the elderly, began to rise from the late 1970s through the early 1990s. At the same time, the incidence of asthma also increased, both nationally and worldwide.

There is no cure for asthma. Although the disease may go through a period of quiescence, it appears that childhood asthmatics do not outgrow the disease as previously believed. Treatment includes inhaled or oral steroids or bronchodilators (albuterol, theophylline), breathing exercises, and, if possible, the identification and avoidance of triggers.

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asthma

[′az·mə]
(medicine)
A pulmonary disease marked by labored breathing, wheezing, and coughing; cause may be emotional stress, chemical irritation, or exposure to an allergen.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.

asthma

a respiratory disorder, often of allergic origin, characterized by difficulty in breathing, wheezing, and a sense of constriction in the chest
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005
References in periodicals archive ?
One study reported that the prevalence of atopic asthma in Indian asthmatics was 55.6% with highest sensitisation to housefly antigen in 31.1% patients and lowest to HDM which was only in 7.8% patients.27 This difference in sensitisation of aeroallergens can be due to regional and environmental differences in indoor and outdoor settings.
Evaluation of Mean Platelet Volume and Other Complete Blood Count Parameters in Children with Atopic Asthma. Bezmialem Science 2018; 6(3): 181-5.
Each of the two probes of mononuclear cells from the BALF of individuals with atopic asthma (n=3) after segmental allergen provocation showed mRNA expression for IL-22 BP and IL-22.
It was a combination of SAR with persistent moderate atopic asthma. It was detected that 5 patients with SAR exhibited a high level ofsensitization to allergen components of both wormwood (w6) and birch (rBet v 1).
This clinical study targeted 130 pediatric patients with mild to moderate atopic asthma, In this clinical research study, special Plasmacluster Ion generators producing an ion concentration of 100,000 ions/cm3 were set up in the home in two rooms where the subjects spent long periods of time selected from among the bedroom, living room, and children's room (nursery).
A single-nucleotide polymorphism in IL-33 that showed a suggestive association with the circulating eosinophil count was also significantly associated with atopic asthma [17].
The relative risk (OR) of a child having atopic asthma if he or she had a mother with or without the exposure variable is set out in Table 2.
The researchers found that childhood eczema, especially in association with childhood rhinitis, is strongly associated with current atopic asthma in middle age.
In a phase II prospective randomized trial, no serious treatment-related adverse events, dose-limiting toxicities, or deaths were reported after a single intravenous dose of Medi-528 or placebo in 30 patients with mild to moderate atopic asthma.
It was indicated that contact with livestock reduced the risk of atopic asthma in children (von Ehrenstein et al.
Genaera Corporation (Plymouth Meeting, PA) announced issuance by the United States Patent and Trademark Office of patent number 7,056,698 entitled "Nucleic Acids Encoding Interleukin-9 Receptor Variants." The patent relates to the diagnosis, treatment and methods for discovery of new therapeutics for atopic asthma and related disorders based on variants of Interleukin-9 (IL-9) receptor.