atopic dermatitis

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atopic dermatitis

[‚ā‚täp·ik ‚dər·mə′tīd·əs]
(medicine)
A chronic eruption of red patches accompanied by intense itching that usually begins in infancy but may continue into adult life; the disease has a genetic predisposition, but its expression is modified by environmental factors.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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of % Infants Children Contact dermatitis 1 14.28% 8 18.60% Atopic eczema 4 57.14% 3 6.97% Hand foot eczema 0 0% 5 11.62% Insect bite allergy 2 28.57% 11 25.58% Seborrheic 0 0% 5 11.62% dermatitis Sweat retention 0 0% 3 6.97% dermatitis Photo allergic 0 0% 2 4.65% dermatitis Others 0 0% 6 13.95% Total 7 43 Table 3.
Evening primrose oil in the treatment of atopic eczema: effect on clinical status, plasma phospholipid fatty acids and circulating blood prostaglandins.
Prevention of CV disease by better control of severe eczema will also mean participants can have access to expensive new biologic drugs that are becoming available for treating atopic eczema.
Increased cardiovascular risks also were seen in individuals whose atopic eczema was active more than half the time at follow-up.
Weidinger et al., "Mutual antagonism of T cells causing psoriasis and atopic eczema," The New England Journal of Medicine, vol.
Of 132 of the children, 35% were later diagnosed with atopic eczema, and the rate in the probiotic group, 23%, was half the 46% rate in the placebo group.
It can be used by adults and pediatric patient aged >2 years with mild to moderate atopic eczema. Open label extension trial with >500 patients from phase 3 trials were conducted in adults and pediatrics.
A complex interaction of genetic, environmental and immunological factors has been implicated in the pathogenesis of atopic eczema. [5] Studies have demonstrated the pivotal role of epidermal barrier dysfunction in AD; it results in the down-regulation of cornified envelope genes, reduced ceramide levels in the stratum corneum (SC), elevated levels of endogenous proteolytic enzymes, and increased TEWL.
Although the pathogenesis of eczema remains obscure, the findings show that IL-18 in supernatants of PBMCs of patients with atopic eczema (AE) was significantly higher and that active IL-18 in sera of patients with AE was enhanced at the exacerbation of their disease [3] suggesting that IL-18 may play a role in eczema.
Early onset of atopic eczema followed by asthma and allergic rhinitis with increased age in childhood were reported in many previous studies [27].
Atopic dermatitis (AD), also known as atopic eczema, is a chronic inflammatory skin disease characterized by eczematous dermatitis and itching.[sup][1],[2],[3] The prevalence of childhood AD ranged from 15% to 30% while adult AD from 2% to 10% in industrialized countries.[sup][4] AD is often associated with other allergic conditions.