atropine


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atropine

atropine (ătˈrəpēn, –pĭn), alkaloid drug derived from belladonna and other plants of the family Solanaceae (nightshade family). Available either as the tincture or extract of belladonna, or as the pure substance atropine sulfate, it is a depressant of the parasympathetic nervous system. It has some chemical similarity to the body substance acetylcholine and interferes with nerve impulses transmitted by that substance. Atropine produces rapid heart rate, dilated pupils, dry skin, and anesthetizes the nerve endings in the skin. Because it relaxes smooth muscle and suppresses gland and mucous secretions, it has been used to treat peptic ulcer by reducing the production of stomach acid. Atropine is given before general anesthesia to keep the air passages clear and is an ingredient in various preparations for symptomatic relief of colds and asthma. It also acts as an antidote in poisoning from such agents as mushrooms, morphine, prussic acid, and nerve gas, but overdosage causes delirium, convulsions, and coma. A related alkaloid, scopolamine, is used mainly as a sedative.
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atropine

[′a·trə‚pēn]
(pharmacology)
C17H23O3N An alkaloid extracted from Atropa belladonna and related plants of the family Solanaceae; used to relieve muscle spasms and pain, and to dilate the pupil of the eye.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.

atropine

, atropin
a poisonous alkaloid obtained from deadly nightshade, having an inhibitory action on the autonomic nervous system. It is used medicinally in pre-anaesthetic medication, to speed a slow heart rate, and as an emergency first-aid counter to exposure to chemical warfare nerve agents. Formula: C17H23NO3
Collins Discovery Encyclopedia, 1st edition © HarperCollins Publishers 2005
References in periodicals archive ?
It's important to know about atropine treatment because many countries, including the United States, are seeing skyrocketing myopia rates.
The early findings are indicating better control of myopic progression using a combination of atropine and ortho-k.
Nishiyama makes an excellent use of heart rate variability as a marker of autonomic activity to compare these drugs; however, we believe atropine injections should have been at the same time.
Both atropine and 2-PAM chloride are available to medical professionals as spring-loaded auto-injector pressurized syringes for IM administration (see Figure 4).
The company said the Diphenoxylate Hydrochloride and Atropine Sulfate Tablets in USP, 2.5 mg/0.025 mg is an AA-rated generic version of the branded product, Lomotil (diphenoxylate hydrochloride and atropine sulfate tablets).
The effects of central nervous system include respiratory depression, seizures and unconsciousness.10-12 The mortality rate slightly declined following intensive management as compared to the past where delay in diagnosis and improper treatment caused more deaths.1,11 The combined therapy of atropine and pralidoxime is the basis of OPP treatment.1,8,9,13 Extracorporeal elimination may be a useful adjunctive strategy.
The patient was tranferred by ambulance on a transport ventilator and with an atropine infusion (0.017 mg/kg/h).
The doctor said adrenaline is used to maintain the heart's activity and blood pressure, while atropine is used to increase the heartbeat in case it slows during surgery and dormicum is used to make patients lose consciousness.
The aim of this study was to investigate the effect of atropine eye drops on choroidal thinning induced by hyperopic retinal defocus, using automated measures of choroidal thickness obtained with swept-source optical coherence tomography (SS-OCT).
Gooi Soon Seng, the lawyer of one of the accused, Siti Aisyah, said the bottles containing atropine and 12 other exhibits were sent by the police to the chemistry department of the Alcohol and Toxicology Clinical Unit for conducting tests March 10.
Then, tissue was exposed to atropine (10 [micro]M) for 2 min, and subsequently, recordings were obtained after exposure to acetylcholine (100 [micro]M) again at 0.5, 1.0, 1.5 and 2.0 min.
On this basis, the objective of the present study was to investigate the effect of pretreatment with atropine and dipyrone, separately or combined, on the effect of hypoglycemia on liquid GE in rats.