autoantibody


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autoantibody

[¦ȯd·ō′ant·i‚bäd·ē]
(immunology)
An antibody formed by an individual against his own tissues; common in hemolytic anemias.
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References in periodicals archive ?
The key application of KREX is the discovery of autoantibody biomarkers for two core medical use cases.
Sengenics Partners with the Foundation for the National Institutes of Health Biomarkers Consortium
The three ZNT8 autoantibody variants together improve the diagnostic sensitivity of childhood and adolescent type 1 diabetes.
Prevalence of ZnT8 Antibody in Turkish Children and Adolescents with New Onset Type 1 Diabetes
In Vermeersch P et al.'s article (1), the anti-centriole pattern was the rarest autoantibody pattern.
Evaluation of Rare Antinuclear Antibody Patterns in a Tertiary Hospital in Izmir
"We are very excited to advance our autoantibody into the clinic with Servier," said professor Adrian Hayday, co-founder of ImmunoQure.
ImmunoQure, Servier
Anti-MDA5 autoantibody levels were measured by qualitative immunoprecipitation assay.
Effect of Adalimumab on Refractory Arthritis in Juvenile Idiopathic Inflammatory Myopathy with Anti-MDA5 Autoantibody
Alternatively, autoantibodies may be generated through the initial damage to myocardial cells by viral infection that releases a large quantity of self-antigens into the circulation, in which case the viral infection is followed by a second phase of immune process of the disease, recruiting active immunocompetent cells into the cardiac tissue that favor B cell activation and subsequent autoantibody production, resulting in myocardium damage and progression of heart disease [89-115].
Roles of Host Immunity in Viral Myocarditis and Dilated Cardiomyopathy
The anti-lgE/anti-FcepsilonRlalpha autoantibody network in allergic and autoimmune diseases.
Potential Tests for an Autoimmune Subgroup of Patients with CFS and MCS Could Help Bring Illness Recognition: Helping to Identify Which Patients May Test Positive
CA-I and CA-II autoantibody levels were measured in serum samples obtained from each of the three groups and compared statistically.
The relationship between serum carbonic anhydrase I-II autoantibody levels and diabetic retinopathy in type 1 diabetes patients
Among the anti-ENA autoantibody subtypes, anti-ACA was seen in 37% of patients, anti-Scl-70 in 24%, anti-RNP in 9%, and anti-RNAPIII in 5%; other subtypes were rarer.
Nailfold analysis predicts cardiopulmonary complications
This study then presents a new model for circulating troponins based on this in-depth evaluation of this interfering autoantibody.
Troponin Autoantibodies: From Assay Interferent to Mediator of Cardiotoxicity
Furthermore, plasma IgA autoantibody levels binding to oxLDL have been shown to be positively and IgG autoantibody levels to be negatively associated with markers of glucose metabolism and also to be independent risk factors for type 2 diabetes [8].
Elevated Levels of Plasma IgA Autoantibodies against Oxidized LDL Found in Proliferative Diabetic Retinopathy but Not in Nonproliferative Retinopathy
Since evidences show that protein overexpression could induce humoral responses in cancer patients [19] and Ezrin proteins were found to be upregulated in ESCC (including early-stage ESCC) in comparison to adjacent normal tissue in our previous study [17], it is plausible that Ezrin might induce autoantibody production in ESCC patients.
Diagnostic Value of Autoantibodies against Ezrin in Esophageal Squamous Cell Carcinoma

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