autoantibody


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autoantibody

[¦ȯd·ō′ant·i‚bäd·ē]
(immunology)
An antibody formed by an individual against his own tissues; common in hemolytic anemias.
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References in periodicals archive ?
More helpful to the clinician is the autoantibody pattern or profile, which multiplex arrays such as NALIA can readily and economically provide.
Screening autoantibody profiles in systemic rheumatic disease with a diagnostic protein microarray that uses a filtration-assisted nanodot array luminometric immunoassay (NALIA)
Cost-effectiveness of an autoantibody test (AABT) as an aid to diagnosis of lung cancer" Sunday, June 6, 2010, 8 a.
Studies Demonstrate Early Stage Detection and Economic Benefits of a Blood-Based Test for Lung Cancer
On the other hand, the results of the dual-label TR-IFMA assay and the RBA assays did not correlate well linearly, mainly because of the limited linear range of the RBA assays at high autoantibody concentrations, especially in the GADA assay, as can be seen from the shapes of the correlation graphs (Fig.
Time-resolved immunofluorometric dual-label assay for simultaneous detection of autoantibodies to GAD65 and IA-2 in children with Type 1 diabetes
It should also be remembered that the remarkably high frequency of decreased recovery of cTnI is related to the fact that cTnI assays aim to measure very small amounts of the antigen, so that even minute autoantibody titers may exert a noticeable inhibitory effect.
Negative interference in cardiac troponin I immunoassays by circulating troponin autoantibodies
One disadvantage of the ELISA and TRIFMA is the higher sample volume required compared with the RBA, particularly for autoantibody determination in newborns.
Evaluation of two nonisotopic immunoassays for determination of glutamic acid decarboxylase and tyrosine phosphatase autoantibodies in serum
CONCORDANCE OF AUTOANTIBODY LEVELS IN CR-CW, CR, AND CW ASSAYS
Diabetes antibody standardization program: first proficiency evaluation of assays for autoantibodies to zinc transporter 8
52,53] This Group has conducted 4 annual workshops from 1988 to 1992; the 1988 and 1989 consensus workshops were conducted to define inter-laboratory concordance when detecting autoantibody specificities in rheumatic diseases.
Human autoimmune diseases: Progress in clinical laboratory tests
today announced that it is hosting a webinar to show participants how they can generate multiplexed autoantibody assay results in a one-step, 15 minute process.
Genalyte To Host Webinar on Chip-Based Multiplex Autoantibody Detection
Number of autoantibodies (against insulin, GAD or ICA512/IA2) rather than particular autoantibody specificities determines risk of type 1 diabetes.
Is diabetes mellitus a continuous spectrum?
Immunization that results in an IgG autoantibody response requires switching of B-lymphocyte class, and therefore CD4 T cells must be involved in addition to naive mature B cells.
Autoimmune markers in diabetes
Oncimmune's EarlyCDT-Lung test has increased the sensitivity of the autoantibody test while maintaining a high level of specificity.
First Reportable Data of EarlyCDT(TM)-Lung Use in Clinical Practice Presented at IASLC World Conference on Lung Cancer
One should consider that an autoantibody to antigen may have a negative (interference) or positive (stabilizing) effect on the measurement of the antigen, and that multiple autoantibody/antigen pairs may act independently.
Coprevalence of autoantibodies to cardiac Troponin I and T in normal blood donors

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