: Patient receives own stem cells.
Also, no researchers had adequately compared protracted consolidation/maintenance chemotherapy--the mainstay of treatment for acute lymphocytic leukemia (ALL)--with autologous transplant
to determine efficacy.
This would be for inherited metabolic disorders that could be corrected by autologous transplant
. In some cases, scientists are now able to manipulate a genetic defect and correct it through the transplantation process.
Tenders are invited for Aggregate supply of bags for collection and filtering autologous transplant
of adipose tissue, 50 ml.
He added: "The important benefit of our approach is that as a therapy, it would be an autologous transplant
. This means that for a patient who suffers a heart attack, we would take a muscle biopsy from his or her muscle, isolate and purify the myoendothelial cells, and re-inject them into the injured heart muscle, thereby avoiding any risk of rejection by introducing foreign cells."
Wesley has undergone seven courses of chemotherapy and on Tuesday received what is known as an autologous transplant
-- About 60% of patients with multiple myeloma achieved complete remission when a conventional autologous transplant
was combined with a nonmyeloablative allogenic transplant, Dr.
The issue of high dose chemotherapy and autologous transplant
is a good example.
The risk of proven and probable IPA among autologous transplant
recipients is quite low (0.5%-1%), as compared to patients undergoing allogeneic HSCT or those treated with induction chemotherapy for acute leukemia (3%-7%) (13-15).
Mozobil, in combination with G-CSF, is designed to release hematopoietic stem cells from the bone marrow into the bloodstream where they can be collected, making it more likely for patients with certain types of cancers to proceed to autologous transplant
. Currently, before a transplant can take place, patients may receive a prescribed dose of chemotherapy and/or growth factors to help mobilize their hematopoietic stem cells into the bloodstream.
"Most of the multiple myeloma (ML) patients age 70 or older are offered less effective non-transplant treatments that in the long run may be more toxic and expensive than a single autologous transplant
. Elderly patients are also excluded from clinical trials so there's little data available on how they respond to transplant," said Muzaffar Qazilbash, MD, associate professor in the department of stem cell transplantation MD Anderson Cancer Center in Houston, TX.
Children at highest risk of late pulmonary sequelae included those transplanted after more than one complete remission, those who received an allogeneic rather than autologous transplant
, and youngsters with a documented pulmonary infection, the researchers said.