Autolysis

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autolysis

[ȯ′täl·ə·səs]
(geochemistry)
Return of a substance to solution, as of phosphate removed from seawater by plankton and returned when these organisms die and decay.
(pathology)
Self-digestion by body cells following somatic or organ death or ischemic injury.

Autolysis

 

self-digestion of animal, plant, and microorganism tissue. In autolysis the cellular proteins, carbohydrates, and fats break down under the action of hydrolytic enzymes in the cells. In living organisms, autolysis is evident in necrotic centers and in cells of malignant neoplasms. Autolysis occurs in decomposing corpses. In plants autolysis occurs after the death of living cells as a result of low temperature, desiccation, and the action of such poisonous substances as chloroform and toluene, as well as during mechanical tissue disintegration. Autolysis of microbe cells is evident in aging microbe cultures and in microorganisms damaged by physical, chemical, or biological agents. Autolysis also occurs in several industrial processes—for example, in tobacco and tea fermentation and during feed storage.

N. P. MESHKOVA

References in periodicals archive ?
The idea of responsibility for the autolytic behavior is provided by the development of the plot in the form of a dialogue, while the hostility and aggressivity of the suicidal person are shot at a person in need of attention and love, whom she curses profusely--that person gradually turning into an empathic alter-ego, a mirror image triggering off the process of growing responsible and painfully aware, now in a poetic idiom, of the huge separation between expectation and reality, between the real person and our mental image of her person.
These factors contribute to the occurrence of spoilage which is caused by three mechanisms: autolytic enzymatic spoilage, oxidative spoilage and microbial spoilage.
To help manage moisture and promote autolytic debridement--the body's way of getting rid of dead tissue and keeping healthy tissue--Medline Industries, Inc.
Notably, this also helps reduce the number of mice that die of old age, in which brain tissue can undergo autolytic deterioration that impairs immunohistochemical (IHC) analyses.
Studies conducted by or for the NTP involve removal of moribund animals to avoid autolytic tissue destruction and to prevent tissue loss through cannibalism (NTP 2011a).
Simple mastectomies without axillary lymph node sampling, specimens showing ductal carcinoma in situ (DCIS) without invasive component, specimens with previous lump removal and then no residual tumour, specimens with previous neo-adjuvant therapy and then fibrosed tumour, specimens with marked autolytic changes and specimens having non- epithelial tumours were excluded.
The increased activities of ALT, AST and ALP reported herein have been attributed to the damaged structural integrity of the liver, because these are cytoplasmic in location and they are released into plasma as result of autolytic breakdown or cellular necrosis into circulation after cellular damage (Recknagel et al.
Whereas base treatment of adsorbent usually destroys autolytic enzymes which are responsible for its degradation and remove lipids and proteins that mask reactive sites [30-32].
Tissue cannot be 'kept' in saline as the latter has no fixative properties and profound autolytic change, rendering the tissue useless, will result.
This includes not using dressings that would cause autolytic debridement.
Subsequently, Hunter and Brennan (25) discovered two other minor phenolic glycolipids, apparent autolytic products of PGL-I, one of which, PGL-III, was chemically defined; it simply lacked the 3-O-methyl substituent of the terminal 3,6-di-O-methyl-glucose of PGL-I.
It also facilitates an autolytic milieu and hence promotes debridement (NHS 2008).