When vestibular function was studied in families with inherited autosomal dominant hearing loss
, vestibular symptoms were not a major complaint, although vestibular loss could be detected in clinical evaluations.
In the article titled "A Novel Nonsense Mutation of POU4F3 Gene Causes Autosomal Dominant Hearing Loss
" , Dr.
Targeted high-throughput sequencing identifies pathogenic mutations in KCNQ4 in two large Chinese families with autosomal dominant hearing loss
. PLoS One 2014;9:e103133.
Autosomal dominant hearing loss
tends to be milder and occur later, often in the second to third decades of life.
It has been recommended to accurately analyze at least three generations in the family tree, especially in the suspicion of an autosomal dominant hearing loss