virus of chickens is divided into various subgroups and recently isolates from indigenous chicken breeds in East Asia were found to be clearly correlated with previously described subgroups (Cui et al., 2014).
Development and application of polymerase chain reaction (PCR) tests for the detection of subgroup J avian leukosis
Western blot antibody reactivity to the p27 gag protein of the endogenous avian leukosis
virus (ALV) in vaccine recipients and other reference chicken and human sera Sera tested p27 Positive Chicken sera (n = 61) ALV infected/antibody positive(a) 27/27 ALV uninfected/antibody negative(a) 0/34 REV infected 0/10 Human sera (n = 68) Blood donors 0/60 HIV-1/2 positive 0/4 HTLV-I/II positive 0/4 MMR vaccine recipients (n = 206) 6-12 months(b) 0/32 12-30 months(b) 0/158 6-12 months(c) 0/16
Virus particles and viral antigens in chicken tissues free of infectious avian leukosis
Witter, because the East Lansing lab was set up in 1939 for a similar crisis - involving less virulent strains of avian leukosis
. In the same spirit of cooperation seen today, Michigan State then donated 50 acres of land for the lab.
Detection of avian leukosis
virus in albumen of chicken eggs using reverse transcription polymerase chain reaction.
(22-26) Avian leukosis
virus causes B-cell lymphomas mainly in gallinaceous poultry, and reticuloendotheliosis virus has been associated with either B- or T-cell lymphomas in gallinaceous birds, geese, and a European starling (Sturnus vulgaris).
(10,11) Severe leukocytosis in birds is often associated with diseases such as aspergillosis, avian mycobacteriosis, salmonellosis, chlamydiosis, and sepsis, (12) but herpesviruses (ie, Marek disease) and retroviruses (ie, avian leukosis
virus, reticuloendotheliosis virus) can specifically cause a lymphocytic leukocytosis in chickens.
Avian lymphoproliferative disorders have been associated with herpesvirus (Marek's disease) and retroviruses (avian leukosis
virus and reticuloendotheliosis virus), (10,18) Some lymphoid neoplasms in psittacine birds are suspected to be caused by viruses because of the resemblance to those syndromes caused by RNA viruses in domestic chickens.
In chickens, lymphoid neoplasia has been associated with infections by a herpes virus (Marek's disease), avian leukosis
virus, and reticuloendotheliosis virus.
Several viral diseases can present with a marked lymphocytic leukocytosis such as avian leukosis
virus, reticuloendotheliosis virus, and Marek disease, (10-14) but they are not generally associated with a strong heterophilic leukocytosis.
Several novel criteria have been tested to assist in the differential diagnosis of tumors induced by Marek's disease virus (MDV) from those induced by avian leukosis
virus (ALV) and reticuloendotheliosis virus (REV).