avidity


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avidity

[ə′vid·əd·ē]
(immunology)
The total binding strength of a polyvalent antibody (an antibody that has multiple binding sites for the same antigen) with a polyvalent antigen (an antigen with multiple identical antibody-binding sites); equivalent to the sum of the affinities at each of the binding sites.
References in periodicals archive ?
"This collaboration with Lilly provides an exceptional opportunity to leverage Avidity's proprietary AOC platform in order to generate new therapeutic targets in disease areas that have been challenging to pursue using oligonucleotide-based approaches," said Kent Hawryluk, Avidity's chief business officer.
Under the terms of the agreement, Avidity will receive an upfront payment of $20 million, as well as an investment of $15 million.
There will be announcements on the latest developments with new products and technology updates, such as the upcoming launch of Watchdog EX, the newest control and monitoring solution offered by Avidity Science.
Although distinguishing between primary and secondary vaccine failure is difficult, detection of mumps antibody with high avidity in a person with mumps suggests secondary failure.
H9N2 viruses commonly have alanine at HA1 position 180 (A180), which correlates with a preference for binding of 3SLN, viruses with glutamic acid (E180) generally show greater binding avidity for 6SLN; and viruses with valine (V180) have been shown to show appreciable binding to 6SLN, together with greater replicative fitness in mammals than viruses with A180 (17,35,36).
Avidity said the acquisition expands its portfolio of water purification solutions to include ion exchange and filtration media and cartridges.
Upon closing, the acquisition expands Avidity Science's range of products and solutions supporting the research tools market and is another step towards its mission of enabling science to improve the quality of life
Of the patients tested for anti-rubella IgG avidity, 92.7% exhibited high avidity (>60%), 3.4% low avidity (<30%), and 3.9% moderate avidity (30-60%).
The avidity indices (AIs) were calculated by comparing the absorbances of the untreated samples and treated samples as following: AI (%) = (absorbance treated sample/ absorbance untreated sample) x 100.
In this study, we observed a relationship between clinical parameters related to TB severity and a change in antibody levels and antibody avidity to Mtb antigens, both before and after treatment.
The aim of the study was to estimate the significance of IgG avidity determination in establishing the diagnosis of WNV infection.