Nearly 30% of patients of Breast Cancer could have been saved of unnecessary axillary dissection
if sentinel lymph node biopsy technique is used.
Is sentinel lymph node biopsy a viable alternative to complete axillary dissection
following neoadjuvant chemotherapy in women with node-positive breast cancer at diagnosis?
The main risk factor that could result in the development of an angiosarcoma is the lack of lymphatic drainage after axillary dissection
due to radiation therapy .
Until 2011, almost all of our patients who had a positive sentinel node underwent axillary dissection
. However, following the publication of the ACOSOG Z11 trial , there were 87 cases (16.3% of the entire group) in which no further lymph nodes were excised.
As high as 48% patients with breast cancer who had undergone axillary dissection
with positive nodes are reported to develop breast edema a year after the surgery .
Sentinel-node biopsy to avoid axillary dissection
in breast cancer with clinically negative lymph-nodes.
Regarding treatment, all patients of TLC underwent MRM with axillary dissection
.  Tubular carcinomas, mixed ductal and lobular carcinoma are the main differential diagnosis of TLC.
Clough et al., "Combined axillary reverse mapping (ARM) technique for breast cancer patients requiring axillary dissection
," Annals of Surgical Oncology, vol.
Many explanations have been proposed, including (1) younger patients were subjected to more aggressive use of adjuvant therapies; (2) age related decrease in pain perception; (3) negative oestrogen receptor status; (4) increased nerve sensitivity; (5) greater surgical invasion in axillary dissection
. For axillary clearance is more challenging because of more fatty tissue [16,17], some researchers consider an elevated BMI as a risk factor for this syndrome, but our results showed no correlation.
(8) reported 50% recurrence rate when the axilla is treated only with radiotherapy (RT) in comparison to axillary dissection
Half of these complications were attributable to axillary dissection
, it is hoped that lower complication rates can be achieved with sentinel lymph node biopsy.
, chemotherapy, and radiotherapy have not been shown to improve the rates of disease-free or overall survival.