axolemma


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axolemma

[‚ak·sə′lem·ə]
(neuroscience)
The plasma membrane of an axon.
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(1976) Intramembranous particle distribution at the node of Ranvier and adjacent axolemma in myelinated axons of the frog brain.
Anti-GM1 antibodies bind to the axolemma at the Ranvier nodes and may induce reversible conduction failure, possibly depending on the intensity of local immune reaction, or to complement deposition (10,11).
Our technique provides a vesicle preparation (vesicles destined for the axolemma) that is free of one of the major contaminants of vesicle preparations: neurofilament proteins.
The target molecules in AMAN are likely to be gangliosides GM1, GM1b, GD1a, and GalNAc-GD1a expressed on the motor axolemma. Rabbits have also been reported to develop a sensory and motor neuropathy following immunization with GD1a and GM1 or LOS extracted by Campylobacter jejuni (C.
IgG and activated complement components bound to the axolemma of the motor nerves in AMAN patients, and that activated complement components bound the outer surface of Schwann cells.