azelaic acid


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azelaic acid

[¦az·ə¦lā·ik ′as·əd]
(organic chemistry)
HOOC(CH2)7CCOH Colorless leaflets; melting point 106.5°C; a dicarboxylic acid useful in lacquers, alkyd salts, organic synthesis, and formation of polyamides.
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The two formulations of azelaic acid have not been subjected to a head-to-head comparison of penetration in human skin, a study that Dr.
Azelaic acid provides an antibacterial effect against P acnes, an anticomedomal effect, and an anti-inflammatory action (Taffe, 1997).
As well as reducing redness and swelling in acneprone skin, products with azelaic acid can also decrease the production of keratin, a protein which can block pores and lead to acne.
Those in group 2 received two laser treatments with the Excel V 532-nm long-pulsed laser plus concurrent daily use of the topical Jan Marini Skin Care Management System, which included a glycolic acid cleanser, vitamin C serum, active containing glycolic, salicylic and azelaic acids, peptide, and growth factor moisturizer and a broad-spectrum sunscreen.
Azelaic acid is used as an exfoliator and cleanser to wash the skin, and is a treatment for acne and rosacea.
A comparison of low-fluence 1064-nm Q-switched Nd:YAG laser with topical 20% azelaic acid cream and their combination in melasma in Indian patients.
Comment: Azelaic acid is a 9-carbon straight-chain dicarboxylic acid that occurs naturally in some foods.
Mild acne can often be treated at the pharmacy using products such as benzoyl peroxide, azelaic acid and salicylic acid, which are applied to the skin to reduce bacterial growth and soften the skin.
Other therapeutic options include azelaic acid 15% gel or 20% cream.
Only data on outcome measures from trials on topical metronidazole, topical azelaic acid, and oral tetracycline could be pooled.
Reed uses erythromycin, benzoperoxide, azelaic acid, clindamycin, or metronidazole.
Other medicines that can reduce acne blemishes include tretinoin (Retin-A), adapalene (Differin), azelaic acid (Azelex), or tazarotene (Tazorac).