azole


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Related to azole: azole antifungals, Echinocandins

azole

[′ā‚zōl]
(organic chemistry)
One of a class of organic compounds with a five-membered N-heterocycle containing two double bonds; an example is 1,2,4-triazole.
References in periodicals archive ?
"Septoria is becoming harder to control with azoles and SDHIs.
A 2013 paper in Plos Pathogens said that it appeared to be no coincidence that drug-resistant Aspergillus was showing up in the environment where the azole fungicides were used.
Aspergillus species and other molds in respiratory samples from patients with cystic fibrosis: a laboratory-based study with focus on Aspergillus fumigatus azole resistance.
Additionally, there were no statistically significant differences between study years or FW and NFW households in the levels of azole fungicides detected in household dust; thus, the azoles will not be discussed in further detail (Tables 2 and 3).
Patients with a concomitant systemic illness, immunosuppression, extensive involvement (>20% body surface area) or known hyper-sensitivity to azole antifungals were excluded from the study.
Azole antifungals are common substrates and inhibitors of the hepatic CYP450 enzymes.
krusei) (14) determino la necesidad de buscar tratamientos alternativos o superiores a los azoles.
Azoles. This class can be subdivided into the older generation imidazoles and the newer generation triazoles, based on the number of nitrogen atoms in the azole ring.
Ketoconazole and posaconazole are both members of the azole antifungal family.