beta-lactamase

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Related to b-lactamase: ESBL

beta-lactamase

[¦bād·ə ′lak·tə‚mās]
(microbiology)
A bacterial enzyme that catalyzes the hydrolysis of the lactam ring in some penicillin antibiotics, rendering them ineffective.
McGraw-Hill Dictionary of Scientific & Technical Terms, 6E, Copyright © 2003 by The McGraw-Hill Companies, Inc.
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A 1998 survey of extended-spectrum b-lactamases in Enterobacteriaceae in France.
KEY WORDS: AmpC b-lactamase detection, Antimicrobial resistance, Multidrug resistant bacteria, Neonatal sepsis.
The occurrence of bacterial infection had decreased with the discovery of penicillin in 1940 until Staphylococcus aureus began producing B-lactamase, which destroys the penicillin B-lactam core ring (Khan, et al., 2013).
Keywords: AmpC b-lactamase, Multidrug resistant Klebsiella pneumoniae, Inhibitor-based method.
Objective: Fast detection of b-lactamase (bla) genes can minimize the spread of antibiotic resistance.
SHV-type extended-spectrum b-lactamase in a Shigella flexneri clinical isolate.
These data confirm the presence of an extended spectrum b-lactamase (ESBL) producing IncHI2 plasmid in strain A54560 that is capable of con jugative transfer and suggest that the plasmid might have been acquired by residual index strain within the patient by transfer from an unknown donor bacterium.
Plasmid-mediated carbapenem-hydrolyzing b-lactamase KPC-2 in Klebsiella pneumoniae isolate from Greece.
The reason for this is that many isolates were determined to be b-lactamase negative in spite of their resistance to some of the antibiotics.